Helicobacter pylori (H. pylori) infection causes a progression to atrophic gastritis and results in gastric cancer. Cytotoxin-associated gene A (CagA), major virulence factor of H. pylori, is injected into epithelial cells using the type IV secretion system. On other hand, degrade CagA an autophagy system, which strictly regulated by autophagy-related (ATG) genes. This study aimed identify SNPs...

Helicobacter pylori (H. pylori) was first identified in 1982 by the Australian physicians Barry Marshall and Robin Warren. is also known as Campylobacter pylori. It a gram-negative, micro-aerophilic, spiral (helical) bacterium usually found stomach. H. infection one of most common chronic bacterial infection, affecting approximately half world's population. Peptic ulcer disease, gastric ulcers,...

AIM To investigate the effect of Helicobacter pylori (H. pylori) status test and H. pylori eradication on the occurrence of metachronous gastric cancer (MGC) after endoscopic submucosal dissection (ESD) of early gastric cancer (EGC) and risk factors of MGC. METHODS The authors retrospectively reviewed the medical records of 433 patients (441 lesions) who underwent ESD for EGC from January 200...

BACKGROUND/AIMS Helicobacter pylori eradication therapy has been used as a first-line treatment for H. pylori-positive gastric mucosa-associated lymphoid tissue (MALT) lymphoma. However, the management strategy for H. pylori-negative MALT lymphoma remains controversial. Therefore, the aim of this study was to examine the success rate of each treatment option for H. pylori-positive and H. pylori...

OBJECTIVE This study was designed to compare the effect of Helicobacter pylori (H. pylori) infection treatment on serum zinc, copper, and selenium levels. PATIENTS AND METHODS We measured the serum zinc, copper, and selenium levels in H. pylori-positive and H. pylori-negative patients. We also evaluated the serum levels of these trace elements after H. pylori eradication. These serum copper, ...

Helicobacter pylori (H. pylori) infections affect roughly one-half of the world’s population. Although many standard regimens, including triple-drug therapy, eradicate H. pylori, success rate and efficacy have been declining due to associated side effects symptom severity. The addition probiotics a regimen can considerably increase eradication rates. objective is find probiotic Lactobacillus re...

Background: Helicobacter pylori (H. pylori), is a common infection in pregnant women accompanied by variations in the levels of the IgM, IgA and IgG antibody isotypes. The variations of anti-H. pylori antibodies during and after pregnancy, and the extent of protection they provide to the mother and the fetus are not completely understood. Objectives: To investigate the changes of the anti-H. py...

Introduction: Recent studies have shown a relationship between H. pylori and chronic idiopathic thrombocytopenic purpura (CITP). Objective: The present study was performed to evaluate this relationship in Iranian patients. Methods:  The antibody (IgG) against H. pylori was studied in sixty-two patients with CITP, comprising 25 males and  37 females (mean age: 30.38±12.23 yrs ) The patients posi...

BACKGROUND Helicobacter pylori (H. pylori) frequently colonizes the stomach. Gastroesophageal reflux disease (GERD) is a common and costly disease. But the relationship of H. pylori and GERD is still unclear. This study aimed to explore the effect of H. pylori and its eradication on reflux esophagitis therapy. METHODS Patients diagnosed with reflux esophagitis by endoscopy were enrolled; base...