Macaca nemestrina have two fetal hemoglobins which differ in the structures of their .y chains. Thus animals of this species, like man, appear to possess duplicate y-chain loci. In this study, the ontogenesis of hemoglobins in M. nemestrina was followed in animals ranging in age from the 60th day of gestation to adulthood. Fetuses in the 60th day of gestation had the two fetal hemoglobins and a...

A number of mutant hemoglobins are inordinately unstable, denaturing in circulating red cells into Heinz bodies, resulting in congenital Heinz body hemolytic anemia (CHBHA). We have emphasized that most such hemoglobins involve amino acid substitutions at sites neighboring the heme group of the beta-polypeptide chain, and have shown that heme binding to globin is diminished thereby. Thus, hemes...

Key to the remarkable ability of vestimentiferan tubeworms to thrive in the harsh conditions of hydrothermal vents are hemoglobins that permit the sequestration and delivery of hydrogen sulfide and oxygen to chemoautotrophic bacteria. Here, we demonstrate that zinc ions, not free cysteine residues, bind sulfide in vestimentiferan hemoglobins. The crystal structure of the C1 hemoglobin from the ...

Hemoglobin is the oxygen transport protein of our cardiovascular system. The tetrameric interfaces in hemoglobin regulate cooperative binding to heme iron present each subunit. Genetic mutations can cause misassembly or impaired stability diseases by altering inter-subunit disrupting subunits. We have performed atomic level molecular dynamics (MD) simulations (Samuel, P.P. and Case, D.A., 2020,...

It has been known that both brain and heart produce magnetic fields however, intensity of field is more. The question arises what the relation between waves. We answer this by suggesting a theoretical model which use hemoglobins other spinors as packages information spin waves for exchanging brain. In model, genes within cells control motions charged ions their spins. By these electrical spinor...

We describe a method of electrophoresis of hemoglobin on cellulose acetate plates impregnated with citrate agar, which remain stable for many months and are used to confirm rapidly the presence of hemoglobins S and C and the hemoglobinopathieS associated with them. The method also provides excellent separations of hemoglobins F and A and reliable identification of genetically determined hemoglo...

For a long time, respiratory proteins have been considered unnecessary in most insects because the tracheal system was thought to be sufficient for oxygen supply. Only a few species that survive under hypoxic conditions were known exceptions. However, recently it has become evident that (1) intracellular hemoglobins belong to the standard repertoire of insects and (2) that hemocyanin is present...

Hemoglobin C and Sickle Cell Hemoglobin By JAIEs V. NEEL, NI.I)., PH.D., EUGENE KAPLAN, M.1),, AND WOLF W. ZUELZER, M.D. I x PREVIOUS COMMUNICATIONS the biochemical, geusetic, ansd (‘linsical aspects of a newly recognsized insherited abnormality of Isemogiohins were briefly descu ibed.n , 2 isew’ hemoglohius, which s ’as insdependenstly desigusated hemoglobins-Ill by Kaplats, Zuelzet’, ansd Xee...