Pulmonary hemosiderosis in infants (< 1 year of age) is a syndrome characterized by pulmonary hemorrhage and hemosiderin-laden macrophages. As there are multiple incompletely understood etiologies regarding this syndrome, this paper discusses the etiologic and pathophysiologic mechanisms, -with particular attention to Heiner’s syndrome, Wegener’s granulomatosis, and the toxigenic mold Stachybot...

Idiopathic pulmonary hemosiderosis is a very rare condition rarely affecting adults and causing recurrent episodes of diffuse alveolar haemorrhage that may lead to lung fibrosis. Due to lack of pathognomonic findings, IPH diagnosis is established upon exclusion of all other possible causes of DAH in combination with specific pathologic findings revealing bland alveolar haemorrhage with absence ...

A two-month-old male with past medical history of recurrent diarrhea and failure to thrive presented with persistent cough, tachypnea and high inflammatory markers despite antibiotic treatment for pneumonia. One week earlier our patient was diagnosed with bilateral pneumonia based on same symptoms as well as chest x-ray findings, and was started on Amoxicillin 80mg/kg/day. There was no fever. P...

INDIAN PEDIATRICS 1056 VOLUME 42__OCTOBER 17, 2005 antibody: negative, immunoglobulin profile: normal, anti-neutrophil cytoplasmic antibody (ANCA) negative, computerized tomography (CT) of chest: alveolar damage with hazy lung fields (Fig. 1). Thoracoscopic lung biopsy displayed multiple nodules of varying sizes on the lung surface, histopathologic examination exhibited alveolar spaces filled w...

Background: In recent years, the success in management of thalassemic patients, has allowed for some previously unrecognized complications including renal abnormalities to emerge. This prospective study aimed to investigate kidney iron overload by means of MRI T2* and also renal function based on laboratory tests for early markers of glomerular and tubular dysfunction among adult Iranian transf...

Disseminated ossification of the lungs is rare. Most of the cases reported in. the literature are associated with mitral stenosis, hemosiderosis and granulomas. Wells and Dunlap,’ in a review of the literature in 1943, stated that about 45 cases of diffuse ossification of the lung unassociated with tuberculous scars had been reported, of which about 35 cases were of the racemose or branching ty...