Objective: The aim of this study was to find out if the process hepatic fibrosis due hepatitis B and C accentuates development lungs. Method: Cases with histories parenchymal biopsies were scanned retrospectively, which had been biopsied diagnoses. Among these patients, those who undergone a computed tomographic (CT) examination chest during year following biopsy procedure investigated for sign...

objective(s):fuzheng huayu recipe (fzhy) exerts significant protective effects against liver fibrosis by strengthening the body’s resistance and removing blood stasis. however, the molecular mechanisms through which fzhy affects liver fibrosis are still unclear. in this study, we examined the expression levels of factors involved in the inhibitor κb kinase-β (ikk-β)/nuclear factor-κb (nf-κb) an...

Chronic liver disease is a progressive deterioration of hepatic functions and continuous process inflammation, destruction, regeneration parenchyma, resulting in fibrosis cirrhosis [...]

an aborted female holstein foetus with marked generalized anasarca was referred to the excellence centre for ruminant abortion and neonatal mortality, ferdowsi university of mashhad. on postmortem examination, red-tinged ascites, pale and firm liver with extreme irregularity and numerous round to oval slightly raised foci on the capsular surface were seen. histological examination revealed wide...

Hepatic fibrosis is a reversible pathological process, in which fibrotic tissue is excessively deposited in the liver during the repair process that follows hepatic injury. Early prevention or treatment of hepatic fibrosis has great significance on the treatment of chronic hepatic diseases. Hydroxysafflor yellow A (HSYA) is a water-soluble monomer extracted from safflower, which serves numerous...

The Fibrosis-4 (FIB4) index could indicate the liver fibrosis in patients with chronic hepatic diseases. It was calculated using following formula: (age × aspartate aminotransferase [U/L]) / (platelet count [103/μL] √alanine [U/L]). However, clinical impact of FIB4 acute phase heart failure (AHF) has not been sufficiently investigated.

Hepatic fibrosis is commonly diagnosed in dogs, often as a sequela to chronic hepatitis (CH). The development of fibrosis is a crucial event in the progression of hepatic disease that is of prognostic value. The pathophysiology of hepatic fibrosis in human patients and rodent models has been studied extensively. Although less is known about this process in dogs, evidence suggests that fibrogeni...

this paper presents four cases of abnormal soft tissue activity in the bone scan of patients with different lesions (lung inflammatory pseudotumor, pulmonary fibrosis, pulmonary metastatic osteosarcoma and metastatic hepatic carcinoma of colon).

Hepatic fibrosis is a leading cause of morbidity and mortality worldwide. Hepatic fibrosis is usually associated with chronic liver diseases caused by infection, drugs, metabolic disorders, or autoimmune imbalances. Effective clinical therapies are still lacking. Autophagy is a cellular process that degrades damaged organelles or protein aggregation, which participates in many pathological proc...

AIM To evaluate the role of tissue factor (TF) and protease activated receptor (PAR)-2 in liver fibrosis. METHODS Using CCl4 administration for eight weeks, we induced hepatic fibrosis in wild-type C57BL/6 mice and in mice with deletion of the cytoplasmic signalling domain of TF (TF§CT/§CT), deletion of PAR-2 (PAR-2-/-) and combined deletion of TF signalling domain and PAR-2 (TF§CT/§CT/PAR-2-...