Hepatocellular carcinoma (HCC) is considered a classic inflammation-associated tumor that usually originates from chronic hepatitis, where an intense and inflammatory response leads to the accumulation of mutations eventually carcinogenesis under conditions persistent liver injury. In recent years, immunotherapy for HCC has continued evolve, as naturally filled with large variety immune cells, ...

DNA methyltransferase 3B (DNMT3B), one of methyltransferases has many roles in methylation and cancer pathogenesis. However, its clinical prognostic value was not studied hepatocellular carcinoma (HCC). In this study, we analyzed DNMT3B expression HCC by public big data, The Cancer Genome Atlas. Primary data about total 360 were downloaded clinicopathological implication analyzed. M stage (p = ...

BACKGROUND More than 50% of the worldwide cases of hepatocellular carcinoma occur in China, and this malignancy currently represents the country's second leading cause of cancer death in cities and the leading cause in rural areas. Despite recent advances in the control and management of hepatocellular carcinoma within China, this disease remains a major health care issue. The global HCC BRIDGE...

Hepatocellular carcinoma (HCC) is the most common, malignant tumor of the liver. Hepatocellular carcinoma (HCC) commonly metastasizes to the lungs, abdominal lymph nodes, adrenal glands, or bones. Distant lymph node metastases are rare in hepatocellular carcinoma. A 49-year-old male patient presented with right sided neck mass. On examination there was right cervical lymphadenopathy and hepatom...

background : data mining has an interdisciplinary field including various scientific disciplines such as: database systems, statistics, machine learning, artificial intelligence and the others. in the field of medical, data mining algorithms can help physicians to diagnose diseases and chose the best type of treatment. hepatocellular carcinoma has the most common type of liver cancer. given the...

Hepatocellular carcinoma (HCC) was the sixth most common cancer and third cause of cancer-related deaths worldwide in 2020. Liver resection transplantation remain cornerstone for patients with early-stage disease represent only option potential cure HCC. However, fewer than 10% are considered suitable surgery at time diagnosis. Locoregional therapies, defined as minimally invasive image-guided ...

Sorafenib is a breakthrough in the medical treatment aiming to control hepatocellular carcinoma (HCC) progression, but there some controversy patients' selection. The introduction of has led several positive effects. New more than promising antiangiogenic molecules have followed. Immunotherapy combined with therapy also strongly entered into HCC. All that induced significant guideline revision ...

Background: Hepatocellular carcinoma (HCC) is a major type of liver tumor. It represents up to 90% all malignancies. There are currently no reliable tumor markers or imaging technologies that can accurately diagnose early HCC. The use circulating micro-RNAs (miRNAs miR) as potential tool for detection HCC has become an emerging area study. Objectives: This study aimed evaluate the role miR-23b ...

Rational:Lymphoepithelioma-like hepatocellular carcinoma (LEL-HCC) is a rare variant of hepatocellular carcinoma (HCC). To date, few cases have been reported in the literature, and almost no report in analyzing the different features of LEL-HCC. Patient concerns: We describe a 37-year-old female patient with a 32 30mm mass in the right liver. Interventions: Complete surgical resection of the le...

AIM To investigate the expression of cysteine-rich61 (Cyr61), connective tissue growth factor (CTGF) and nephroblastoma overexpressed gene (Nov) in hepatocellular carcinoma (HCC), and to evaluate the relationship between Cyr61, CTGF and Nov genes expression with invasion and metastasis of HCC. METHODS Thirty-one HCC specimens were divided into small hepatocellular carcinoma (SHCC), nodular he...