In addition to the steady flow of new cytotoxic drugs for lung cancer during the last decade, the elegant concept of targeted agents has in recent years become a source of optimism and pitfalls. Among all the targets, Her2-neu is a typical example of how preclinical data can be translated into clinical progress. Her2-neu in breast cancer: the ideal model Erb-B2 (Her2-neu) is a 185 kDa glycoprot...

Background: Magnetic resonance imaging (MRI) mammography has been recommended as a problem solving tool in patients with breast lump for which newer protocols like abbreviated, ultrafast MRI and diffusion are now available. For interpretation lexicons BIRADS Kaiser score system available but there is scope improvement of results need lexicons.Methods: Retrospective study 175 who had was done. T...

Malignant trichoepithelioma (MTE) or matrical carcinoma is a neoplastic change of matrical and inner root sheet cells. It is generally described in dogs, with no sex predisposition. In this case, a glassy skin mass was taken from a 8-year-old, female mixed breed cat. Histopathologically, it was presented with the typical matrical cells islands, central keratinisation and necrosis, hyalinated co...

The successful application of human gene therapy protocols on a broad clinical basis will depend on the availability of in vivo cell-type-specific gene delivery systems. We have developed retroviral vector particles, derived from spleen necrosis virus (SNV), that display the antigen binding site of an antibody on the viral surface. Using retroviral vectors derived from SNV that displayed single...

Background Neoadjuvant chemotherapy has been used as a primary treatment for locally advanced or inflammatory breast cancer, and recently extended to operable breast cancer. The aim of this study was to evaluate the predictive value of different histologic factors in breast cancer treated with neoadjuvant anthracycline chemotherapy in Tunisian women. Methods A total of 109 stage II and III br...

Background: Breast cancer despite being the 2nd most commonly diagnosed, with around 68,50,00 deaths globally in 2020, has only handful of resources on baseline characteristics, along clinical features and histopathological findings India. Methods: A retrospective study was done among 52 patients who presented breast proven histologically, having identified nodal status by histopathology. All d...