In the context of research in the broad area of nutrition and cancer, a major new discovery was made during 1976, quite recently, when T. Sugimura (National Cancer Center, Tokyo, Japan) observed the un expected presence of considerable mutagenicity at the surface of grilled or broiled fish or meat, using the usual procedures of cooking such foods. Isolation and identification of the mutagens sh...

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Heterocyclic compounds are of very much interest in our daily life. Heterocyclic compounds have one or more hetero atoms in their structure. They may be cyclic or non cyclic in nature. Heterocyclic compunds have a wide range of application. They are predominantly used as pharmaceuticals, as agrochemicals and as veterinary products. They also find applications as sanitizers, developers, antioxid...

Cross-coupling of aromatic aldehydes or benzoins with unactivated imines catalyzed by an N-heterocyclic carbene (NHC) affords alpha-amino ketones smoothly.

The aromaticity of some bicyclic heterocycles is discussed with the aid of the configuration analysis of the expansion coefficient matrices and the similarity analysis of the density matrices. The iso-it-electronic [9] annulenyl anion is taken as the aromatic reference compound for all the heterocyclic compounds considered. The restflts are compared with · those previously obtained from conside...

Homoenolates generated from enals by nucleophilic heterocyclic carbene (NHC) catalysis undergo a conjugate addition/cyclization sequence with cyclic dienones, culminating in the efficient synthesis of spirocyclopentanones.

Heterocycles have vital interest in the pharmaceuticals and agrochemicals. Synthetic chemistry provides wealth of heterocyclic systems. More than 90% of drugs contain heterocycles ring and the interface between chemistry and biology. Scientific insight, discovery and applications are taking place by heterocyclic compounds. This review article covers theactive heterocycles that have shown consid...

Recent investigations have shown the oxone-mediated oxidative methyl esterification of benzaldehyde derivatives using methanol. The reactions were accelerated in the presence of indium(III) triflate, a trivalent indium reagent, in many cases. Based on this method of methyl esterification of benzaldehyde derivatives, we further explored an application to heterocyclic aldehydes. The reactions wer...

A series of heterocyclic acene diimides were synthesized effectively based on the condensation of o-phenylenediamine, 1,2-benzenedithiol, and 2-aminothiophenol with 2,3,6,7-tetrabromo-1,4,5,8-naphthalene tetracarboxylic diimide. The diimides exhibit interesting optical and electrical properties with one of them showing a hole mobility up to 0.02 cm(2) V(-1) s(-1).