Classic Epidemiology: High-Density Lipoprotein Cholesterol Is a Biomarker of Atherogenic Lipoproteins and Other Major Cardiovascular Risk Factors High-density lipoprotein (HDL) cholesterol is a robust biomarker of atherosclerotic cardiovascular disease (CVD) events. In observational studies and many clinical trials of statin therapy, HDL cholesterol levels are inversely associated with CVD even...

In vitro interactions of purified lipoprotein lipase with plasma from type IV hyperlipidemic and normolipidemic subjects were studied using an automated cholesterol analysis adaptation to single vertical spin centrifugation. Lipolysis for 60 min of normolipidemic plasma (control) supplemented with autologous very low density lipoprotein (VLDL) resulted in a progressive conversion of VLDL to low...

Classic Epidemiology: High-Density Lipoprotein Cholesterol Is a Biomarker of Atherogenic Lipoproteins and Other Major Cardiovascular Risk Factors High-density lipoprotein (HDL) cholesterol is a robust biomarker of atherosclerotic cardiovascular disease (CVD) events. In observational studies and many clinical trials of statin therapy, HDL cholesterol levels are inversely associated with CVD even...

To investigate the effects of chronic ethanol administration on the mobilization and excretion of cholesterol, turnover and balance studies were carried out in baboons pair-fed cholesterol-free diets containing 50% of energy either as ethanol or as additional carbohydrate for several years. Ethanol feeding increased free cholesterol in all plasma lipoprotein fractions, and esterified cholestero...

We investigated the relation of plasma lipids to the risk for ischemic stroke by comparing clinical and biochemical characteristics of survivors of cortical (n = 48) and lacunar (n = 36) brain infarction. By analysis of variance, no differences were observed in the concentrations of total cholesterol, triglycerides, low density lipoprotein cholesterol, very low density lipoprotein cholesterol, ...

Overview: Lipoproteins are spherical particles that carry lipids, particularly cholesterol and triglyceride, in the plasma. There is a well-established association between dyslipidemias, or disorders of lipoprotein metabolism, and coronary heart disease (CHD): elevated levels of blood cholesterol, especially low-density lipoprotein cholesterol (LDL-C), and low levels of high-density lipoprotein...

BACKGROUND High levels of the triglycerides to high-density lipoprotein cholesterol (TG/HDL-C) ratio are associated with obesity, metabolic syndrome, and insulin resistance. OBJECTIVES We evaluated variability in the remaining lipid profile, especially remnant lipoprotein particle cholesterol (RLP-C) and its components (very low-density lipoprotein cholesterol subfraction 3 and intermediate-d...

Objective(s): Hypercholesterolemia is a common metabolic disorder in developing and developed countries and is associated with the increased rates of chronic kidney disease (CKD). Statin therapy could reduce cholesterol synthesis as well as progression of CKD. Diversity between statins causes variety in pharmacokinetics and pharmacodynamics and also their pleiotropic e...

The term plasma lipid profile considers measurement of certain components of plasma including total cholesterol (TCh), high density lipoprotein cholesterol (HDL-Ch), triglycerides (Tg), low density blipoprotein cholesterol (LDL-Ch) and very low density lipoprotein cholesterol (VLDL-Ch). TCh consists of all the cholesterol present in different lipoproteins like high density lipoprotein (HDL), lo...

OBJECTIVE To evaluate abnormal lipid metabolism as a risk factor of eclampsia in pregnant women. METHODS This cross sectional study was conducted in three tertiary care hospitals of Peshawar. Serum total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), very low density lipoprotein cholesterol (VLDL-C), triglyceride (TG), apolipoprote...