نتایج جستجو برای: histidine rich protein ii

تعداد نتایج: 1864136  

2014
Maria Ranieri-Raggi Arthur J. G. Moir Antonio Raggi

Metallochaperones function as intracellular shuttles for metal ions. At present, no evidence for the existence of any eukaryotic zinc-chaperone has been provided although metallochaperones could be critical for the physiological functions of Zn2+ metalloenzymes. We propose that the complex formed in skeletal muscle by the Zn2+ metalloenzyme AMP deaminase (AMPD) and the metal binding protein his...

Journal: :Antimicrobial agents and chemotherapy 2004
Harald Noedl Paktiya Teja-Isavadharm Robert Scott Miller

A simple, nonisotopic, semiautomated bioassay for the measurement of antimalarial drug levels in plasma or serum based on the quantitation of histidine-rich protein II in malaria culture is presented. The assay requires only small sample volumes and was found to be highly sensitive and reproducible. The results closely paralleled those obtained with isotopic bioassays (R = 0.988, P < 0.001) and...

2015
Claribel Murillo Solano Sheila Akinyi Okoth Joseph F. Abdallah Zuleima Pava Erika Dorado Sandra Incardona Curtis S. Huber Alexandre Macedo de Oliveira David Bell Venkatachalam Udhayakumar John W. Barnwell Richard Culleton

A number of studies have analyzed the performance of malaria rapid diagnostic tests (RDTs) in Colombia with discrepancies in performance being attributed to a combination of factors such as parasite levels, interpretation of RDT results and/or the handling and storage of RDT kits. However, some of the inconsistencies observed with results from Plasmodium falciparum histidine-rich protein 2 (PfH...

Journal: :International journal of tropical diseases 2021

Diagnosis of malaria is a fundamental component case management. Parasitological confirmation before treatment was recommended for endemic countries. Microscopy diagnosis malaria, the gold standard as constraints such as: level expertise, quality equipment and reagents may lead to misdiagnosis. The histidine rich protein 2 (HRP-2) based rapid diagnostic test (RDT) detects Plasmodium falcipa...

Journal: :Organic & biomolecular chemistry 2011
Bin Wang Yang Gao Hong-Wei Li Zhi-Peng Hu Yuqing Wu

A new probe/Cu(2+) complex for the detection of his-tagged protein has been developed, based on an improved probe, Dansyl-Gly-Py (1), by closely mimicing the structure of a peptide, ATCUN. In aqueous solution, 1/Cu(2+) has good selectivity to histidine and cysteine, and further can detect histidine-rich protein by releasing the quenched fluorescence of 1.

Journal: :Indian journal of medical microbiology 2006
D K Mendiratta K Bhutada R Narang P Narang

Rapid diagnosis is a prerequisite for institution of effective treatment and reducing the mortality and morbidity of falciparum malaria. This study was taken up to compare the efficacy of various rapid methods viz, acridine orange, Plasmodium falciparum histidine rich protein II antigen detection and Field's stain with traditional microscopy i.e, Leishman stain for diagnosing falciparum malaria...

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