In the article, the actions of homocysteine (Hcys) and its metabolite - cyclic thioester - homocysteine thiolactone (HTL) on complex process of hemostasis, which regulates the flowing properties of blood, are described. Possible interaction of Hcys and HTL with endothelial cells, blood platelets, plasmatic fibrinogen and plasminogen, as the important major components of hemostasis are also disc...

the purpose of this study was to investigate the effect of short term creatine monohydrate supplementation on baseline homocysteine concentrations and following an exhaustive exercise in active men. twelve male students who were members of soccer team of mazandaran university (age: 21.83±2.20 years, bmi: 13.53±58 kg/m2, homocysteine: 13.53±58 ?mol/lit) volunteered to participate in this study. ...

To investigate the relationship between obstructive sleep apnea hypopnea syndrome complicated with various traditional Chinese medicine syndromes of hypertension and plasma homocysteine level, patients were divided into liver-fire excess syndrome, yin deficiency yang phlegm-blood stasis based on type standard syndrome. General data, body mass index values, index, oxyhemoglobin saturation, Epwor...

The role of homocysteine role in inflammation and malignancy has been studied experimentally. Some researchers suggest that a relationship exists between pancreatitis and homocystinuria, possibly being secondary to occlusive vascular disease of the pancreas. To date, plasma homocysteine levels in pancreatic disease have not been studied. We aimed to analyze the homocysteine status in patients w...

elevated total plasma homocysteine (thcy) levels constitute a risk factor for coronary artery disease (cad). a possible relationship was investigated between admission plasma homocysteine level and the angiographic severity and extension of coronary artery disease in patients with cad. this study looks at the relationship between total plasma homocysteine and severity of coronary artery disease...

Homocysteine, a cardiovascular and neurocognitive disease risk factor, is converted to hydrogen sulfide, a cardiovascular and neuronal protectant, through the transsulfuration pathway. Given the damaging effects of free homocysteine in the blood and the importance of blood homocysteine concentration as a prognosticator of disease, we tested the hypotheses that the blood itself regulates homocys...

background: it is well documented that coronary artery bypass grafting (cabg) with cardiopulmonary bypass (cpb) causes ischemia and oxidative stress of the whole body. to compare the effect of on – pump and off –pump cabg on the induction of the oxidative stress and the metabolism of homocysteine which is involved in the synthesis of glutathione was investigated in the cabg patients during the ...

Background. Homocysteine is a sulfur-containing amino acid that can have damaging effect on the vascular endothelium, being an independent risk factor for development of cardiovascular pathology. The purpose. To evaluate functional state endothelium in hyperhomocysteinemia children with arterial hypertension. Material and methods. 111 aged 14 to 18 years were examined. All patients divided into...