abstract background: asterocytoma is the most common primary human brain tumor which has the most lethal hazard among tumors in human central nervous system. heat shock proteins play an active role in cancer cells pathways through their effects on tumor cell proliferation, tumor differentiation, malignancy, metastasis, and cell death. hsp 70 is a 70 kd protein that its expression change has bee...

henoch–schönlein purpura (hsp), a common allergic hemorrhagic disease, occurs frequently in children affecting kidney, joint and skin. while interleukin-8 (il-8) plays an important role in inflammation, the association between il-8 gene +781 c/t polymorphism and hsp remains unclear. interleukin-8, an important chemokine related to the initiation and amplification of acute inflammatory responses...

Pretreatment with heat decreases mortality and acute lung injury in the rat septic shock model, presumably by the production of heat shock proteins (HSP). However, endotoxin, a severe cell stresser, has not been shown to induce HSP 70. We investigated the effects of severe endotoxemia on the expression of specific protective stress proteins, including HSP 72 (inducible HSP 70), HSP 32 (heme oxy...

During a 6 year period from September 1992 to September 1998, 165 children with a final diagnosis of Henoch-Schonlein purpura (HSP) were managed and followed in our center. There were 87 (52%) boys and 78 (48%) girls, with age ranges of 1-16 years and mean age of 7.8 years. Forty-one percent of the patients had evidence of preceding upper respiratory tract infection (URI). The main clinica...

Background In children with Henoch-Schonlein purpura (HSP), the severity of Henoch-Schonlein purpura nephritis (HSPN) is considered responsible for the prognosis of HSP. The pathological process from HSP to HSPN is not clear yet and current diagnostic tools have shortcomings in accurate diagnosis of HSPN. This study aims to assess clinical characteristics of HSP and HSPN, to identify metabolic ...

Heat-induced accumulation of hsp 30 mRNA (1.1 kb) during early development of Xenopus laevis was first detectable at the tailbud stage (stage 30-34). This contrasts with heat-induced accumulation of hsp 70 mRNA (2.7 kb) and ubiquitin mRNA (size range = 1.7-3.1 kb), which was first detectable at the mid- to late-blastula stage. Continuous exposure of tadpoles to a 33 degrees C heat shock resulte...

Henoch-Schonlein purpura (HSP) is a self-limited autoimmune disease, the cause of which is not clear. Gastrointestinal involvement is often the main symptom of HSP. We report an unusual and rare case in a patient who was diagnosed with HSP. This is the second report of terminal ileitis induced by HSP that presented as acute appendicitis. We report a 21-year-old man who presented with right lowe...

Pathophysiological stimuli, including hypoxia, lead to K(+) efflux from the intracellular lumen to the extracellular space, thereby increasing local tissue K(+) concentrations and depolarizing resident cells. In this study, we investigated the effects of increased extracellular K(+) concentrations ([K(+)](e)) on heat shock protein (HSP) expression in the porcine proximal tubule epithelial cell ...

Elevation of Th2 cytokine-driven inflammatory mediators has been reported in acute stage of Henoch-Schönlein purpura (HSP). However, the temporal interaction between Th2-mediated allergic diseases and HSP with renal involvement remains unknown. Herein, we conducted a population-based cohort analysis to investigate the risk of HSP and renal involvement in children with atopic dermatitis (AD) as ...