Organic redox capacitors using neutral aqueous electrolyte solutions are environmentally friendly and safe. In this study, we report on the fabrication of an all-organic capacitor NaCl solution. We used a 2,2,6,6-tetramethylpiperidinyl-N-oxyl (TEMPO) benzene derivative (4-hydroxy TEMPO benzoate, HTB) 9,10-anthraquinone (AQ) as active materials for positive electrode negative electrode, respecti...

OBJECTIVES This study investigated prognostic significance of tumor budding in early-stage cervical cancer (ESCC) following radical surgery and its contribution to improve the stratification of patients with recurrence risk. METHODS The archival medical records and H&E-stained slides of 643 patients with IA2-IIA stage cervical cancer who underwent radical surgery were retrospectively reviewed...

We have recently developed the HB tag as a useful tool for tandem-affinity purification under native as well as fully denaturing conditions. The HB tag and its derivatives consist of a hexahistidine tag and a bacterially-derived in vivo biotinylation signal peptide, which support sequential purification by Ni2+ -chelate chromatography and binding to immobilized streptavidin. To facilitate taggi...

The multidrug transporter, initially identified as a multidrug efflux pump responsible for resistance of cultured cells to natural product cytotoxic drugs, is normally expressed on the apical membranes of excretory epithelial cells in the liver, kidney, and intestine. This localization suggests that the multidrug transporter may have a normal physiological role in transporting cytotoxic compoun...

The mechanism of lithium insertion that occurs in an iron oxyfluoride sample with a hexagonal-tungsten-bronze (HTB)-type structure was investigated by the pair distribution function. This study reveals that upon lithiation, the HTB framework collapses to yield disordered rutile and rock salt phases followed by a conversion reaction of the fluoride phase toward lithium fluoride and nanometer-siz...

Morphology is the study of internal structure of words and is an essential early step in many NLP applications such as parsing and machine translation. Researchers working in Hindi NLP have either used the widely popular paradigm based analyzer (PBA) or extensions of it. In this work, we undertook a comprehensive evaluation of PBA using the data from the Hindi Treebank (HTB) and presented a new...

Like many big science projects, the Large Synoptic Survey Telescope (LSST) has multiple geographic locations among which large amounts of data must be transferred. One particular type of data, crosstalk-corrected images, must be moved from South America to North America under stringent deadline requirements. LSST is provisioning an international network with bandwidth guarantees to handle this ...

Cytokines play an important role in activating the immune system against malignant cells. One of these cytokines, interleukin-4 (IL-4) has entered clinical phase I trials because of its immunoregulatory potency. In the present study we report that recombinant human (rh) IL-4 has major direct antiproliferative effects on one human lung cancer cell line (CCL 185) in vitro as measured by a human t...

How the immune system attacks medulloblastoma (MB) tumors effectively is unclear, although natural killer (NK) cells play an important role in immune defense against tumor cells. Interactions between receptors on NK cells and ligands expressed by tumor cells are critical for tumor control by immunotherapy. In this study, we analyzed tumor samples from 54 MB patients for expression of major hist...

Gallic acid is a trihydroxybenzoic acid, also known as 3,4,5-trihydroxybenzoic acid, which is present in plants worldwide, including Chinese medicinal herbs. Gallic acid has been shown to have cytotoxic effects in certain cancer cells, without damaging normal cells. The objective of the present study was to determine whether gallic acid is able to inhibit human cervical cancer cell viability, p...