BACKGROUND Vitiligo is a chronic skin disorder. White macules caused by melanocyte destruction is a characteristic finding that cosmetically disturbing. Until recently, pathogenesis of vitiligo is still unclear. The role of homocysteine in vitiligo is mentioned in previous studies thus it is probable that it can be a biomarker to determine vitiligo severity. AIM To determine correlation betwe...

BACKGROUND Vitiligo is a hypopigmentation disorder affecting 1 to 4% of the world population. Fifty percent of cases appear before the age of 20 years old, and the disfigurement results in psychiatric morbidity in 16 to 35% of those affected. METHODS Our objective was to complete a comprehensive, systematic review of the published scientific literature to identify natural health products (NHP...

Abstract This structure proposes the creation of optical biosensor that can be used to detect vitiligo caused pigment loss. For accomplishing this, a pair 2-D photonic crystal structures, such as K3 and K7 resonators, are examined. The study both resonator structures is succeeded using (FDTD) Finite Difference Time Domain. Lumerical simulation tool model these in Domain (FDTD). subsequent prope...

Cholecalciferol (vitamin D) might play a physiological role in photo-induced melanogenesis in human skin. We estimated the levels of 25-hydroxy vitamin D [25(OH)D] before, during, and after Narrow Band Ultraviolet B (NBUVB) radiation in patients of vitiligo and their correlation with NBUVB induced pigmentation. Thirty patients of vitiligo and equal number of age and sex matched controls were re...

The aim of our study was to determine the epidemiological and clinical aspects of vitiligo in the largest dermatology department of Senegal. A cross-sectional and descriptive study in a period of 5 months was performed covering all the vitiligo cases. Fifty patients were identified (26 women and 24 men). The mean age was 26.5 years. A family history of vitiligo was found in 11 cases and a psych...

background: segmental vitiligo is a small subset albeit persistent form of focal vitiligo with dermatomal distribution and resistant to medical therapy. in recent years, surgical therapy as hair follicle autograft transplantation has been a hot topic in management of segmental vitiligo. in this study, we evaluated the efficacy of this method in segmental vitiligo lesions. methods: the study rec...

BACKGROUND The onset of vitiligo during childhood is common. Limited data exist that compare the clinical associations of prepubertal and postpubertal vitiligo in Arabs. OBJECTIVE To compare the clinical profile of pre and postpubertal onset vitiligo. METHODS A cross-sectional observational study was conducted. The Vitiligo European Task Force questionnaire was completed for each patient. ...

Introduction There are a few studies showing an increased risk of insulin resistance, metabolic syndrome, and oxidative stress in patients with vitiligo. Aim To investigate whether systemic inflammation is increased in vitiligo patients in a case-control study design. Material and methods Nonsegmental vitiligo patients who had been followed at the outpatient dermatology clinic of a universi...

PURPOSE Vitiligo prevalence and its associated comorbidities rate have been reported variably among different populations. We aimed to determine the prevalence of vitiligo in Korea along with the baseline rate of comorbidities and compared the risks to the general population using hospital visit information of the total population in Korea. MATERIALS AND METHODS We assessed demographic charac...

Vitiligo vulgaris is an acquired depigmenting disorder resulting from the loss of melanocytes in the skin. Though several putative susceptibility loci of vitiligo have been identified in different populations, the pathogenesis of the disease remains poorly understood. Through genetic linkage analysis of a large Chinese family cohort of vitiligo, we identified a vitiligo linkage locus AIS4 withi...