The retina has a high rate of oxygen consumption, and the retinal vessels are knoion to constrict with increased arterial oxygen tension and dilate ivhen arterial oxygen falls. In 10 subjects, measurement of retinal venous oxygen saturation by a photographic technique has shown an increase from 55 ± 8 per cent saturation breathing air to 82 ± 9 per cent breathing 100 per cent Os. This increase ...

BACKGROUND The first goal was to test the hypothesis that 100% inspired oxygen maintained for approximately 8 h intraoperatively is not associated with impaired pulmonary oxygenation. The authors also tested the hypothesis that intraoperative inhalation of 100% oxygen augments proinflammatory and antimicrobial responses of alveolar macrophages during anesthesia and surgery. METHODS The author...

The aim of this study was to determine whether low-dose inhalation of nitric oxide (NO) improves pulmonary haemodynamics and gas exchange in patients with stable idiopathic pulmonary fibrosis (IPF). The investigation included 10 IPF patients breathing spontaneously. Haemodynamic and blood gas parameters were measured under the following conditions: 1) breathing room air; 2) during inhalation of...

OBJECTIVE To evaluate the alterations of heart rate, blood pressure, psychological aspects and oxygen saturation after continuous fenoterol inhalation (0.5 mg/Kg) by children with severe acute asthma. METHODS We studied 30 patients with severe acute asthma who were treated at the pediatric ward of Hospital Universitário-UFMS. The patients inhaled 0.5 mg/Kg of fenoterol (two drops/Kg) during o...

Inhalation of partially ionized oxygen may have less adverse effects on lung functions than medical oxygen. Guinea pigs inhaled air, 100% molecular medical oxygen (O(2)mol), partially negatively (O(2)neg) or positively (O(2)posit) ionized oxygen during 17 and 60 h. After 17 h, dityrosines, markers of oxidative injury, in lung homogenate increased in O(2)neg and decreased in O(2)posit groups vs....

Atkins JL, Johnson KB, Pearce FJ. Cardiovascular responses to oxygen inhalation after hemorrhage in anesthetized rats: hyperoxic vasoconstriction. Am J Physiol Heart Circ Physiol 292: H776–H785, 2007. First published October 20, 2006; doi:10.1152/ajpheart.00381.2006.— Oxygen inhalation is recommended for the initial care of trauma victims. The improved survival seen in early hemorrhage is norma...

1. Cerebral blood flow, oxygen and glucose consumption, hind-limb blood flow and oxygen consumption, blood pressure and heart rate were measured in seven ventilated dogs. 2. Inhalation of 5% C 0 2 caused a significant increase in cerebral blood flow and a significant decrease in cerebral glucose utilization. 3. Isoprenaline infusion (0.4 pg kg-I min-') caused a rise in cerebral blood flow, oxyg...

BACKGROUND Inner retinal oxygenation response (ΔPO(2)) is a worldwide study focus. However, the relevant reports on its radiological measurements are limited. In this study, magnetic resonance imaging (MRI), employing T1 weighted image (T1WI), was used to detect changes in ΔPO(2) following 100% oxygen inhalation in human subjects. METHODS MRI was performed on a 1.5-T GE scanner system. After ...

BACKGROUND Adrenomedullin (AM) is a potent pulmonary vasodilator peptide. However, whether intratracheal delivery of aerosolized AM has beneficial effects in patients with idiopathic pulmonary arterial hypertension remains unknown. Accordingly, we investigated the effects of AM inhalation on pulmonary hemodynamics and exercise capacity in patients with idiopathic pulmonary arterial hypertension...