Next to the shortest path distance, the second most popular distance function between vertices in a graph is the commute distance (resistance distance). For two vertices u and v, the hitting time Huv is the expected time it takes a random walk to travel from u to v. The commute time is its symmetrized version Cuv = Huv + Hvu. In our paper we study the behavior of hitting times and commute dista...

The Simulcheck method for evaluating the accuracy of color simulation tools in relation to dichromats is described and used to test three color simulation tools: Variantor, Coblis, and Vischeck. A total of 10 dichromats (five protanopes, five deuteranopes) and 10 normal trichromats participated in the current study. Simulcheck includes two psychophysical tasks: the Pseudoachromatic Stimuli Iden...

Expression of follicle-stimulation hormone receptor (FSHR) is confined to gonads and at low levels to some extragonadal tissues like human umbilical vein endothelial cells (HUVEC). FSH-FSHR signaling was shown to promote HUVEC angiogenesis and thereafter suggested to have an influential role in pregnancy. We revisited hereby the expression and functionality of FSHR in HUVECs angiogenesis, and w...

Previous reports have provided evidence to support the view that the de novo synthesis of bradykinin (BK) B(1) receptor is involved in the induction of vascular responses in human umbilical vein (HUV). In the present study, we evaluated different pharmacological tools to further analyze this up-regulation process in HUV. Concentration-response curves to des-Arg(9)-BK, a selective BK B(1) recept...

We determine the computational complexity of several dmision p r o b lerns related to hamiltonian-connected graphs. In particular, we show that it is NP-complete to determine whether a graph G is harniltonian-connected. We also show that it is NP-complete to determine whether G is hamiltonian-connerted from a distinguished vertex u . Lastly, we consider the complexity of multiple-solution and u...

Background/Aim. A substantial line of evidence indicates that Kv4.2 and Kv4.3 channels are the major components rapid transient-outward potassium currents (A-type cur-rents). It is speculated those may be involved in maintenance membrane potential, as well regulation propagation frequency action potentials. However, very little known about presence function A-type human vascular smooth muscles ...

OBJECTIVE To assess the role claudin-5, an endothelial cell (EC) tight junction protein, plays in establishing basal permeability levels in humans by comparing claudin-5 expression levels in situ and analyzing junctional organization and function in 2 widely used models of cultured ECs, namely human dermal microvascular (HDM)ECs and human umbilical vein (HUV)ECs. METHODS AND RESULTS By immuno...

An association between platelets, angiogenesis, and cancer has long been recognized, but the mechanisms linking them remains unclear. Platelets regulate new blood vessel growth through numerous stimulators and inhibitors of angiogenesis by several pathways, including differential exocytosis of angiogenesis regulators. Herein, we investigated the differential release of angiogenesis stimulators ...