Af-Hydroxy-1-aminonaphthalene (JV-hydroxy-1-AN), N-hydroxy-2-aminonaphthalene (N-hydroxy-2-AN), 1-aminonaphthalene (1-AN), 2-aminonaphthalene (2-AN), and 2-amino1,4-naphthoquinone were repeatedly injected i.p. into rats at a dose of 5 mg/100 gm. Lower doses of 2-amino-l-naphthol (0.15 mg/100 gm), and of #-hydroxy-aniline (1.3 mg/100 gm) were also given i.p. ./V-Hydroxy-1-AN was a more potent ca...

The total synthesis of two natural phenolglycosides of the family Salicaceae, namely: populoside and 2-(β-d-glucopyranosyloxy)-5-hydroxy benzyl (3-methoxy-4-hydroxy) cinnamoate and nine not found yet in plants acyl derivatives of phenoglycosides: 2-(β-d-glucopyranosyloxy)-benzylcinnamoate, 2-(β-d-glucopyranosyloxy)-benzyl (4-hydroxy) benzoate, 2-(β-d-glucopyranosyloxy)-benzyl (3-methoxy-4-hydro...

The Front Cover shows one of the three types hydrogen bonding observed in hydroxy-functionalized halide salts. Here, anion forms a bond to hydroxy group and interacts with ring system cation at same time. versatility structures demonstrates importance non-covalent interactions, particular role bonding. More information can be found Communication by Ralf Ludwig co-workers.

Untargeted metabolomics identified urinary biomarkers able to discriminate between the intake of fresh hand-squeezed and industrially processed orange juices. Processing led an upregulation in excretion hydroxy-polymethoxyflavone sulfates, abscisic acid, sinapic acid 4′-glucuronide. The demethylated polymethoxyflavone metabolites were produced with a significant interindividual variability sugg...

considering multiple reports on cytotoxic activity of the artemisia genus and its phytochemicals, in the current study a. armeniaca lam. and the three components isolated from the plant were subjected to cytotoxic studies. analytical fractionation of a. armeniaca aerial parts for the first time was directed to the isolation of 7-hydroxy-8-(4-hydroxy-3-methylbutoxy) comarin (armenin), 8-hydroxy-...

The effect of hydroxy substitution on 1,4-naphthoquinone toxicity to cultured rat hepatocytes was studied. Toxicity of the quinones decreased in the series 5,8-dihydroxy-1,4-naphthoquinone greater than 5-hydroxy-1,4-naphthoquinone greater than 1,4-naphthoquinone greater than 2-hydroxy-1,4-naphthoquinone, and intracellular GSSG formation decreased in the order 5,8-dihydroxy-1,4-naphthoquinone gr...

In the hydrogen-bonding networks of 8-hydroxy-5-hydroxymethyl-3,6-dioxatricyclo[6.3.1.0(1.5)]dodecan-2-one and 5,7-bis(hydroxymethyl)-3,6-dioxatricyclo[5.3.1.0(1.5)]undecan-2-one, both C11H16O5, layers and double strands, respectively, lead to the formation of chains connected by hydroxy-to-hydroxy contacts, where the hydroxymethyl group, present in both structures, acts as a donor. The seconda...