OBJECTIVE The prevalence of hyperprolactinemia in non-functioning pituitary macroadenomas (NFPMAs) is not well known, and hyperprolactinemia caused by a NFPMA is currently associated with diagnostic uncertainty. Thus, the aim of this study was to evaluate the prevalence of hyperprolactinemia in NFPMAs. METHODS A meta-analysis of all existing articles in PubMed was conducted. The search string...

Our group (Horner KC, Guieu R, Magnan J, Chays A, Cazals Y. Neuropsychopharmacology 26: 135-138, 2002) has earlier described hyperprolactinemia in some patients presenting inner ear dysfunction. However, in that study, it was not possible to determine whether hyperprolactinemia was a cause or an effect of the symptoms. To investigate the effect of hyperprolactinemia on inner ear function, we fi...

Use of antipsychotic agents has been associated with hyperprolactinemia, or elevated prolactin levels; this hormonal abnormality can interfere with the functioning of reproductive, endocrine, and metabolic systems. As antipsychotic agents are increasingly used for both United States Food and Drug Administration-approved and nonapproved indications, many individuals are at risk for developing an...

INTRODUCTION Hyperprolactinemia is an uncommon cause of erectile dysfunction in men. Paget's disease of the skull is a relatively common disease. This case proposes a rare example of a causative link between the two and how treatment of the Paget's disease with bisphosphonates helped the patient regain erectile function. CASE PRESENTATION A 67-year-old man with Paget's disease of the skull pr...

Both hyperprolactinemia and depressive disorder are known manifestations of hypothyroidism. However, hyperprolactinemia with overt symptomatology per se has not been reported to precede all episodes of organic depressive disorder. We report a similar presentation.

Background: Hyperprolactinemia and subclinical hypothyroidism may be associated are usually accompanied by menstrual disorders in female patients. The objective of this study is to determine the prevalence association hyperprolactinemia clinical features.
 Materials Methods: This a hospital-based descriptive cross-sectional conducted from 1 July 2022 31 December 2022. Serum Prolactin level...

BACKGROUND/AIM There is a lack of data on the effects of prolactin on calcium metabolism and bone turnover in hyperprolactinemia of various origins. The aim of this study was to compare the influence of medicamentous and physiological hyperprolactinemia on bone turnover in female rats. METHODS Experimental animals (18 weeks old, Wistar female rats) were divided as follows: the group P - 9 rat...

Hyperprolactinemia is increasingly prevalent in patients with common psychiatric disorders due to increasing prescriptions of antipsychotics, particularly newer atypical neuroleptics, in these patients. However, measurement of prolactin levels is indicated only in symptomatic patients. When hyper-prolactinemia is diagnosed, work-up should include exclusion of other causes of hyperprolactinemia,...