Hypertensive disorder in pregnancy (HDP) is one of the major cause of maternal and perinatal mortality & morbidity worldwide particularly in developing countries. In developed countries, maternal mortality rate varies from 4-40 per 1 lakh live birth. In developing countries, it varies from 100-700 with India having 178 per 1 lakh live birth. Objective: Study of biochemical markers and uterine a...

H ypertension is a heterogeneous disorder with a number of welldefined as well as putative etiologies. The World Health Organization estimates that hypertension may cause 7.1 million premature deaths and 4.5% of the disease burden worldwide. Hypertension is a major risk factor for stroke and cardiovascular diseases, and is thus associated with significant morbidity and mortality. Hypertensive h...

Objective: To determine the frequency of miscarriage, hypertensive disorder pregnancy, placental abruption and preterm birth in women with first trimester threatened miscarriage. Study Design: Cross-sectional study. Setting: Department Obstetric & Gynaecology, Sir Syed Hospital Pakistan Naval Ship Shifa (Karachi). Period: April, 2021 to March, 2022. Material Methods: Ninety two 18-40 year o...

The angiotensin-converting enzyme (ACE) inhibitory peptide NCW derived from Mizuhopecten yessoensis has been demonstrated to have significant in vivo anti-hypertensive effect, however, its mechanism is still not fully clarified. This study established a UPLC-Q-TRAP-MS/MS-based widely targeted kidney metabolomics approach explore the changes of metabolic profiles and clarify in spo...

the purpose of this research was to formulate and systemically evaluate in-vitro and in-vivo performances of mucoadhesive propranolol hydrochloride microspheres for its potential use in the treatment of hypertension, myocardial infraction and cardiac arrhythmias. propranolol hydrochloride mucoadhesive microspheres, containing carbopol-934p as mucoadhesive polymer and ethyl cellulose as carrier ...

background: previous studies have indicated that ramadan fasting has beneficial effects on cardiovascular risk factors, specially blood pressure and heart rate. in the present study, the effect of ramadan fasting on 24-hour ambulatory blood pressure and heart rate has been investigated. materials and methods: this prospective observational study was conducted on two groups of individuals. six p...