References 1. Rahman S, Salehin F, Iqbal A: In vitro antioxidant and anticancer activity of young Zingiber offincinale against human breast carcinoma cell lines. BMC Complement Altern Med 2011, 11:76. 2. Ghasemzadeh A, Jaafar HZE: Antioxidant potential and anticancer activity of young ginger (Zingiber officinale Roscoe) grown under different CO2 concentration. J Medicinal Plants Research 2011, ...

The radiation environment on board the space shuttle and the International Space Station includes high-Z and high-energy (HZE) particles that are part of the galactic cosmic radiation (GCR) spectrum. Iron-56 particles are considered to be one of the most biologically important parts of the GCR spectrum. Tissue-equivalent proportional counters (TEPCs) are used as active dosimeters on manned spac...

On exploratory class missions to other planets astronauts will be exposed to types and doses of radiation that are not experienced in low earth orbit. While it is likely that the crew will consist of both male and female astronauts, there has been little research on the effects of exposure to space radiation on central nervous system function and cognitive performance in female subjects. Becaus...

Ion beam transport theory allows testing of material transmission properties in the laboratory environment generated by particle accelerators. This is a necessary step in materials development and evaluation for space use. The approximations used in solving the Boltzmann transport equation for the space setting are often not sufficient for laboratory work and those issues are the main emphasis ...

The aim of the study was to investigate the contribution of secondary particles (mainly neutrons) in producing radiation damage to electronic devices and to astronaut-dose onboard of the International Space Station (ISS). Especially: • To optimize solid state nuclear track detector (SSNTD) assemblies, have been used earlier for neutron dosimetry around nuclear facilities [1,2], for space dosime...

The use of high linear energy transfer (LET) ionizing radiation (IR) is progressively being incorporated in therapy due to its precise dose localization and relative biological effectiveness. At the same time, these benefits particle become a risk for astronauts case inevitable cosmic exposure. Nonetheless, DNA Damage Response (DDR) activated via complex damage healthy tissue, occurring from su...

The nematode Caenorhabditis elegans was exposed to natural space radiation using the ESA Biorack facility aboard Spacelab on International Microgravity Laboratory 1, STS-42. For the major experimental objective dormant animals were suspended in buffer or on agar or immobilized next to CR-39 plastic nuclear track detectors to correlate fluence of HZE particles with genetic events. This configu...

Space travel beyond the Earth’s protective magnetic field will involve exposure of astronauts to irradiation by high-energy nuclei such as Fe, which are a component of galactic cosmic rays. These particles have high linear energy transfer (LET) and are expected to irreversibly damage cells they traverse. Exposure to HZE radiation may therefore cause progressive deterioration of brain function, ...

Exposing young rats to particles of high-energy and charge (HZE particles) enhances indices of oxidative stress and inflammation and disrupts the functioning of the dopaminergic system and behaviors mediated by this system in a manner similar to that seen in aged animals. Previous research has shown that diets supplemented with 2% blueberry or strawberry extracts have the ability to retard and ...