Internal carotid artery dissection (ICAD) is frequently treated with anticoagulation. Objections against anticoagulation are based on solely theoretical concerns of progressive intramural haematoma.We describe a patient with progressive stenoocclusion of the internal carotid artery (ICA) due to intramural haematoma as a possible complication of immediate heparin treatment in ICAD. Heparin dosag...

We study cross-correlations in irregularly spiking systems. A single system displays spiking sequences that resemble a stochastic (Poisson) process. Linear coupling between two systems leaves the inter-spike interval distribution qualitatively unchanged but induces cross-correlations between the units. For strong coupling this leads to synchronization as expected but for weak coupling, both a g...

OBJECTIVE To introduce the imaging characteristics of moyamoya disease (MMD) using high-resolution magnetic resonance imaging (HR-MRI) and to discuss the role of HR-MRI in differentiating MMD from other intracranial artery diseases, especially intracranial atherosclerotic disease (ICAD). DATA SOURCES This review was based on the data in articles published between 2005 and 2015, which were obt...

BACKGROUND AND PURPOSE Diagnosis of Moyamoya disease (MMD) is based on the characteristic angiographic findings. However, differentiating MMD from intracranial atherosclerotic disease (ICAD) is difficult. We compared vessel wall imaging findings on high-resolution magnetic resonance imaging between MMD and ICAD. METHODS High-resolution magnetic resonance imaging was performed on 32 patients w...

The DNA fragmentation factor (DFF) is composed of two subunits, the 40-kDa caspase-3-activated nuclease (DFF40/CAD) and its 45-kDa inhibitor (DFF45/ICAD). During apoptosis, DFF-40/CAD is activated by caspase-3-mediated cleavage of DFF45/ICAD. Mutational analysis of DFF40/CAD revealed that DFF40/CAD is composed of a C-terminal catalytic domain and an N-terminal regulatory domain. Deletion of the...

RATIONALE AND OBJECTIVES The clinical utility of interactive computer-aided diagnosis (ICAD) systems depends on clinical relevance and visual similarity between the queried breast lesions and the ICAD-selected reference regions. The objective of this study is to develop and test a new ICAD scheme that aims improve visual similarity of ICAD-selected reference regions. MATERIALS AND METHODS A l...

For the ICAD conference 2004 in Sydney a sonification of ECG and other data was carried out to merge the boundaries between artistic sonification and scientific auditory display. Listen (Awakening) attempts to create in sound the activity of the brain becoming aware of a piece of music and gradually building in its subconscious reaction and appreciation. Certain constraints were put on the soni...

BACKGROUND Intracranial atherosclerotic disease (ICAD) is the most common ischemic stroke subtype globally. It accounts for 30-50% of all ischemic strokes in Asians. AIMS The aim of the study is to report the frequency of asymptomatic ICAD and its associated Magnetic Resonance Imaging (MRI) findings. METHODS 200 adult participants were recruited from the Radiology Departments of two major d...

Both Staphylococcus epidermidis and Staphylococcus aureus are important causes of infections associated with catheters and other medical devices. It has recently been shown that not only S. epidermidis but also S. aureus can produce slime and carries the ica operon responsible for slime production. In the operon, coexpression of icaA and icaD is required for full slime synthesis. In this study,...