Insulin receptor substrate-1 (IRS-1) is a multi-domain protein that mediates signal transduction from receptors for insulin and other growth factors to a variety of downstream molecules through both tyrosine-phosphorylation-dependent and -independent interactions. While the tyrosine-phosphorylation-dependent interactions mediated by IRS-1 have been well characterized, the molecular basis underl...

 Abstract— Satellite Remote sensing with repetitive and pan viewing and multispectral capabilities, is a powerful tool for mapping and monitoring the ecological changes. Analysis of the remote sensing data is faced with a number of challenges ranging from type of sensors, number of sensors, spectral responses of satellite sensors, resolutions in different domains and qualitative and quantitati...

Signalling by the insulin receptor substrate (IRS) proteins is critically dependent on the tyrosine phosphorylation of specific binding sites that recruit Src homology 2 (SH2)-domain-containing proteins, such as the p85 subunit of phosphoinositide 3-kinase (PI 3-kinase), the tyrosine phosphatase SHP-2 and the adapter protein Grb2. Here we show that stimulation by insulin of freshly isolated pri...

Business applications composed of heterogeneous distributed components or Web services need mediation to resolve data and process mismatches at runtime. This paper describes mediation in IRS-III, a framework and platform for developing WSMO-based Semantic Web Services. We present our approach to mediation within Semantic Web Services and highlight the role of WSMO mediator types when solving mi...

This study has been undertaken to measure land cover change in Kinwat wildlife sanctuary, Nanded using NDVI. Remote Sensing and Image processing technologies enable us cope with the objectives of detection. Most changes vegetation are happening earth close proximity human inhabitations. Study is carried out analyze detect past present conditions area multi temporal remote sensing data IRS-LISS-...

In 1321N1 astrocytoma cells, stimulation of the IGF-1 (insulin-like growth factor-1) receptor increased the association of PI3K [phosphoinositide (PI) 3-kinase] activity with IRS-1 (insulin re-ceptor substrate 1), and increased the cellular concentration of PtdIns(3,4,5)P3. Carbachol, acting on M3 muscarinic receptors, inhibited insulin-, but not PDGF (platelet-derived growth factor)-, stimulat...

This article proposes a novel framework of resource allocation in multi-cell intelligent reflecting surface (IRS) aided non-orthogonal multiple access (NOMA) networks, where an IRS is deployed to enhance the wireless service. The problem joint user association, subchannel assignment, power allocation, phase shifts design, and decoding order determination formulated for maximizing achievable sum...

This paper considers a two-user downlink transmission in intelligent reflecting surface (IRS) aided network over fading channels. Particularly, non-orthogonal multiple access (NOMA) and two orthogonal (OMA) schemes, namely, time division (TDMA) frequency (FDMA), are studied. The objective is to maximize the system average sum rate for delay-tolerant transmission. We propose adjustment dynamic p...

In this paper, an intelligent reflecting surface (IRS) assisted cooperative non-orthogonal multiple access and mobile edge computing (NOMA-MEC) system is proposed, where a base station sends signals to users through the virtue of IRS. When direct links between user are blocked, offloading tasks will be refracted near-end IRS forwarded remote user, equipped with MEC server working at full duplex...