نتایج جستجو برای: il 12
تعداد نتایج: 702529 فیلتر نتایج به سال:
IL-12 p40 homodimer, but not IL-12 p70, induces the expression of IL-16 in microglia and macrophages
Cancer immunotherapy (passive or active) involves treatments which promote the ability of the immune system to fight tumor cells. Several types of immunotherapeutic agents, such as monoclonal antibodies, immune checkpoint inhibitors, non-specific immunomodulatory agents, and cancer vaccines are currently under intensive investigation in preclinical and clinical trials. Cancer vaccines induce pe...
The interleukin (IL)-12 family, which is composed of heterodimeric cytokines including IL-12, IL-23, and IL-27, is produced by antigen-presenting cells such as macrophages and dendritic cells and plays critical roles in the regulation of helper T (Th) cell differentiation. IL-12 induces IFN-γ production by NK and T cells and differentiation to Th1 cells. IL-23 induces IL-17 production by memory...
The occurrence of multiple infections within the human body, such as gastroenteritis, is observed in a subset patients who also experience inflammation-related conditions like ulcerative colitis. Traditionally, these have been associated with an excessive response from Th2 or Th1 cells, respectively. However, recent studies unveiled noteworthy revelation in. context Inflammatory Bowel Disease (...
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