This paper presents a novel tuning algorithm for fractional order IMC controllers for time delay processes. The tuning algorithm is based on computing the equivalent controller of the IMC structure and imposing frequency domain specifications for the resulting open loop system. A second order time delay process is used as a case study. An integer order IMC controller is designed, as well as a f...

The current study is a descriptive and analytical research which aimed at studying the phenomenon of social network building which takes place in cyberspace, in order to comprehend its fundamentals in IMCs (Internet-Mediated Communities). This way, we wanted to identify the reasons of success and describe the life cycle of such communities. The research general goal was that of identifying the ...

Tumor growth is associated with the accumulation of immature myeloid cells (ImC), which in mice are characterized by the expression of Gr-1 and CD11b markers. These cells suppress Ag-specific CD8+ T cells via direct cell-cell contact. However, the mechanism of immunosuppressive activity of tumor-derived ImC remains unclear. In this study we analyzed the function of ImC isolated from tumor-free ...

Purpose – The purpose of this paper is to investigate the effects of reflow time, reflow peak temperature, thermal shock and thermal aging on the intermetallic compound (IMC) thickness for Sn3.0Ag0.5Cu (SAC305) soldered joints. Design/methodology/approach – A four-factor factorial design with three replications is selected in the experiment. The input variables are the peak temperature, the dur...

T cell tolerance is a critical element of tumor escape. However, the mechanism of tumor-associated T cell tolerance remains unresolved. Using an experimental system utilizing the adoptive transfer of transgenic T cells into naive recipients, we found that the population of Gr-1+ immature myeloid cells (ImC) from tumor-bearing mice was able to induce CD8+ T cell tolerance. These ImC accumulate i...

INTRODUCTION The high cost of critical care resources has resulted in strategies to reduce the costs of ruling out low-risk patients by developing intermediate care units (IMCs). The aim of this study was to compare changes in total hospital costs for intensive care patients before and after the introduction of an IMC at the University Hospital Maastricht. METHODS The design was a comparative...

Cell division in Toxoplasma gondii occurs by an unusual budding mechanism termed endodyogeny, during which twin daughters are formed within the body of the mother cell. Cytokinesis begins with the coordinated assembly of the inner membrane complex (IMC), which surrounds the growing daughter cells. The IMC is compiled of both flattened membrane cisternae and subpellicular filaments composed of a...

ancer Res pose: Platelet-derived growth factor α (PDGFRα) is highly expressed in primary prostate cancer and ated skeletal metastases. Here, we tested whether targeting this receptor could impair metastatic ization and progression, as well as prolong survival, either as primary or as combination therapy. erimental Design: We used a preclinical animal model of metastasis in which PC3-ML human te...

In the current era of “minimal treatment” and “personalized” multi-disciplinary management for breast cancer, the data from thousands of women participating in the Regional Nodal Irradiation (RNI) trials has raised several concerns and opened up debate surrounding internal mammary chain (IMC) irradiation. These issues include the relative contribution of irradiation of the IMC, the target volum...

The inner membrane complex (IMC) of apicomplexan parasites contains a network of intermediate filament-like proteins. The 14 alveolin domain-containing IMC proteins in Toxoplasma gondii fall into different groups defined by their distinct spatiotemporal dynamics during the internal budding process of tachyzoites. Here, we analyzed representatives of different IMC protein groups across all stage...