نتایج جستجو برای: immune response antigens
تعداد نتایج: 1215143 فیلتر نتایج به سال:
Immune checkpoint inhibitors (ICIs) have transformed the management of advanced renal cell carcinoma (RCC), but most patients still do not receive a long-term benefit from these therapies, and many experience off-target, immune-related adverse effects. RCC is also different other ICI-responsive tumors, as it has only modest mutation burden, total neoantigen load does correlate with ICI response...
Dendritic cells (DCs) are key regulators of the immune system; they capture antigens and then can either stimulate an immune response or induce tolerance. Our aim was to activate individual DC signaling pathways to regulate the immune response. We therefore expressed constitutive activators of mitogen-activated protein kinase (MAPK) pathways or the interferon pathway, together with tumor antige...
One of the most common outcomes of pulp inflammation is periapical granuloma formation. Existence of immune cells in these lesions showed involvement of both humoral and cellular immunity in the site. The presence of different antigens in the root canal causes production o various antibodies and consequent immunological reactions. Different theories have been proposed on periapical cysts. The m...
vasectomy is one of the extensively used methods of contraception in family planning programs. antisperm antibodies (asa) develop after vasectomy which can result in auto-immune male infertility. the precise sperm antigens involved in the autoimmune response are still poorly defined, therefore we determined the circulating asa and identified relevant sperm antigens based on localization of bind...
BACKGROUND Although immune responses directed against antigens from the intestinal microbiota are observed in certain diseases, the normal human adaptive immune response to intestinal microbiota is poorly defined. OBJECTIVE Our goal was to assess the adaptive immune response to the intestinal microbiota present in 143 healthy adults and compare this response with the response observed in 52 c...
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