Serum factors reactive with human heart or extracts of human heart have been found by a number of investigators utilizing a variety of immunologic techniques (1-7). Kaplan, Meyeserian, and Kushner (8) have demonstrated reactive factors in the sera of patients with acute rheumatic fever and certain other diseases by an immunofluorescent technique. The present study, using the immunofluorescent m...

Immunohistochemical localization of factor VIII-related antigen was studied in human tissues obtained at autopsy or renal biopsy, umbilical cord vessels, smears of washed blood cells and cultured human endothelial cells. Factor VIII-related antigen was demonstrated in the vascular intima throughout the body and cells lining the sinusoids of the lymph node, spleen and liver by an indirect immuno...

there are many effective chemothereutic agents used in influenza disease which some of them inhibit virus replication by interfering with fluv (influenza virus) viral binding or its penetration into cell membrane. a series of polyoxometalates compounds such as pom-523 and pm-504 have been synthesized and have showed inhibitory effects on viruses. in this study we examined anti influenza activit...

ABH antigens are not expressed on the red blood cells of monkeys, making it difficult to accurately determine their blood type. In this study, we evaluated the feasibility, convenience, and stability of two non-invasive methods for ABO typing (a reverse gel system assay and a buccal mucosal cell immunofluorescent assay) in cynomolgus monkeys (n = 72). The renal tissue immunofluorescent assay wa...

Chikungunya virus was quantitatively assayed by counting immunofluorescent foci after infection of BHK21/C13 cell monolayers. The speed and efficiency of virus attachment to cells were markedly enhanced when augmented by centrifugal force. By this procedure, a proportionality was obtained between the number of immunofluorescent foci and the volume of inoculum. Virus penetration into cells was l...

Smith and Israel (1967a, 1967b, 1968) and Goldman and associates (Goldman and Girard, 1968; Girard, Goldman, Baumstark, and Stickle, 1967) have recently reported that spiral organisms, some of which are motile, can be demonstrated in the aqueous humour (AH), cerebrospinal fluid (CSF), and tissues of adequately treated syphilitic patients. Most of these organisms are morphologically indistinguis...