Background: In developed or developing countries, the most common cancer in women is breast cancer with a pick in 40-50 years in Asia. Herein, we compared the association between IHC with FISH in HER2-positive breast cancer patients and affection of trastuzumab on disease free survival and overall survival (OS). Subjects and Methods: Immunohistochemical (IHC) analysis of hormone receptors and H...

Aims: the aim of this study is RPD3 expression in clinicopathological characteristics CRC patients and to existence a relationship between HPV samples Iraqi patients. Material methods: 30 formalin-fixed, paraffin-embedded archival tissues from were obtained, together with 10 normal tissue (free cancer), for immunohistochemical analysis expression. Results: Immunohistochemical (IHC) staining rev...

Background and Objective: Identification of cytogenetic and molecular changes plays an important role in acute myeloid leukemia (AML) patients. Thus, they are used in classification, prognosis and treatment of the disease. The CD123 expression and FLT3 gene mutations are also the variations that may assist in prognosis and treatment of patients with AML.Methods:</...

BACKGROUND Hirschsprung's disease (HD) is one of the most common motility disorders in pediatric age groups and it is very important that it be differentiated from other types of motility disorders, especially intestinal neuronal dysplasia B (IND B). Although many studies regarding the differences between the two disorders by immunohistochemical studies exist, there is as yet no consistent resu...

AIMS To evaluate the sensitivity and specificity of serological, immunohistochemical, and molecular methods in the diagnosis of post kala-azar dermal leishmaniasis (PKDL). METHODS Twenty five patients with confirmed PKDL and 25 controls were included in the study. G2D10, a monoclonal antibody against Leishmania, was used for the immunohistochemical (IHC) staining of lesion sections to visuali...

Purpose. The histological diagnosis of Mycobacterium tuberculosis (MTB) remains a diagnostic challenge despite different methods. Immunohistochemistry (IHC) not only could confirm granulomatous tissue involvement but also can demonstrate MTB antigen immunolocalization. This study tries to clarify the details of immunohistochemical staining for MTB with pAbBCG. Materials/Methods. Twenty-three co...

Introduction: CD-14 is an antigen found on the bladder cancer cells that mediated development by providing a supportive inflammatory microenvironment. The study investigates association of CD14 expression in with demographic factors, clinicopathological parameters and recurrent cases immunohistochemical (IHC) method. Methods: A retrospective using 59 formalin-fixed paraffin-embedded tissue urot...

BACKGROUND American tegumentary leishmaniasis (ATL) is endemic in Latin America, where Brazil has over 27 thousand cases per year. The aim of the present study was to develop an immunohistochemical method (IHC) for ATL diagnosis. For this purpose, we used serum from a dog naturally infected with Leishmania (L) infantum (canine hyperimmune serum) as the primary antibody, followed by a detection ...

Pleomorphic sarcomas (PS) are a heterogeneous group of poorly differentiated malignant neoplasms mesenchymal origin affecting various organs and tissues, which account for 5–7% all soft tissue tumors. PS most often affects the tissues extremities, while being extremely rare in orbital region eyeball. The final diagnosis is given after histological immunohistochemical (IHC) test supplemented by ...