نتایج جستجو برای: immunomodulation therapy
تعداد نتایج: 656734 فیلتر نتایج به سال:
Extracellular Vesicle Mimetics vesicles mimetics (EVMs) prepared from top-down approaches exhibit superiority both in production and biological properties as potential alternatives of extracellular (EVs). By extruding through membrane filters with decreased pore sizes, EVMs can be produced a large scale. In article 2200142, Chenhui Gu, Liqing Shangguan, Xianfeng Lin co-workers summarize the pre...
Emerging data suggest that locoregional cancer therapeutic approaches with oncolytic viruses can lead to systemic anti-tumour immunity, although the appropriate targets for intratumoral immunomodulation using this strategy are not known. Here we find that intratumoral therapy with Newcastle disease virus (NDV), in addition to the activation of innate immunity, upregulates the expression of T-ce...
Endometrial cancer affects the uterus and is becoming increasingly common deadly. Although surgery adjuvant pelvic radiotherapy can often cure disease when it contained in uterus, patients with metastatic or recurrent have limited response rates to chemotherapy, targeted agents, hormonal therapy. To address this unmet clinical need, innovative treatment strategies are needed, a growing focus on...
Endometrial cancer is the only gynecologic malignancy with a rising incidence and mortality. While cure is routinely achieved with surgery alone or in combination with adjuvant pelvic radiotherapy when disease is confined to the uterus, patients with metastatic or recurrent disease exhibit limited response rates to cytotoxic chemotherapy, targeted agents, or hormonal therapy. Given the unmet cl...
The secondary effects of chemotherapy, with bone marrow depression and risk of leukopenia, has traditionally been considered being detrimental for the immune system. However, growing evidence suggests a main role for chemotherapy in antitumor immunomodulation. With reference to cisplatin, which is the basis of neoadjuvant chemotherapy in muscle invasive bladder cancer, four different aspects of...
Photomediated immunotherapy explored to combine the anti-cancer effect of phototherapy with immune enhancement ability immunotherapy, and shown great prospects for cancer treatment strategies. However, photomediated triggered antitumor immunity through release tumor antigens damage-associated molecular patterns from necrotic cells was not enough mighty improve therapeutic benefits due immunosup...
Preventing untoward immune responses against a specific antigen is a major challenge in different clinical settings such as gene therapy, transplantation, or autoimmunity. Following intramuscular delivery of recombinant adeno-associated virus (rAAV)-derived vectors, transgene rejection can be a roadblock to successful clinical translation. Specific immunomodulation strategies potentially leadin...
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