BACKGROUND The ischemic preconditioning response among elderly patients is known to be lower than in adult patients. Since mitochondrial ATP-sensitive potassium (K(ATP)) channels exert preconditioning effects, we undertook this study to determine whether this attenuated activation of K(ATP) channels influences the reduced responsiveness of elderly patients to ischemic preconditioning. METHODS...

With sensory reweighting, reliable sensory information is selected over unreliable information during balance by dynamically combining this information. We used system identification techniques to show the weight and the adaptive process of weight change of proprioceptive information during standing balance with age and specific diseases. Ten healthy young subjects (aged between 20 and 30 yr) a...

To dissociate the effects of age and hearing impairment on changes in frequency selectivity, auditory filter shapes were measured at 2 kHz in four groups of subjects: (1) normal-hearing young subjects; (2) normal-hearing elderly subjects; (3) elderly hearing-impaired listeners; and (4) young normal-hearing listeners with simulated hearing losses. Filter shapes were derived using a modified vers...

The Health Care Financing Administration, in cooperation with other agencies of the Department of Health and Human Services, conducted surveys in 1982 and 1984 designed to develop a better understanding of the number and circumstances of functionally impaired elderly persons living in the community. This report is based on data from the 1982 Long-Term Care Survey. There were approximately 5 mil...

Human auditory steady-state responses (ASSRs) were recorded using stimulus rates of 78-95 Hz in normal young subjects, in elderly subjects with relatively normal hearing, and in elderly subjects with sensorineural hearing impairment. Amplitude-intensity functions calculated relative to actual sensory thresholds (sensation level or SL) showed that amplitudes increased as stimulus intensity incre...

OBJECTIVES to compare the domiciliary service receipt of cognitively impaired and equally dependent physically impaired elderly women prior to the passing of the UK Community Care Act. METHODS secondary analysis of a population survey conducted in 1986 in the city of Cambridge. The analysis used data on 1585 women aged 75 and over living in the community. The effect of type of impairment on t...

Immunosenescence contributes to the decreased ability of the elderly to control infectious diseases, which is also reflected in their generally poor response to new antigens and vaccination. It is known that the T cell branch of the immune system is impaired in the elderly mainly due to expansion of memory/effector cells that renders the immune system less able to respond to new antigens. B lym...

Involuntary weight loss is a symptom of protein energy malnutrition often reported among elderly people, especially those with dementia. In this study, we examined whether dementia-related eating difficulties increase the probability of weight loss in the elderly. This cross-sectional observation study was conducted in 60 community-dwelling elderly people with dementia (84.1±6.7 yr of age). Ove...

Objective: to carry out an integrative review of the literature on risk factors associated with falls among elderly people living in community. Methods: where descriptors were used: elderly, factors, accidents due and aging MeSH terms, Scielo, Pubmed VHL bases, a temporary cut 5 years (2016-2021). After research, 17 references selected that related object study. Results: The most frequent were:...