To what extent is learnability impeded when information is missing in learning instances? We present relevant known results and concrete open problems, in the context of a natural extension of the PAC learning model that accounts for arbitrarily missing information.

Presbyopia, which manifests from loss of accommodative function of the crystalline lens, is a ubiquitous visual disability of the aging eye. The demand for clear, comfortable near vision is increasing with the widespread use of devices such as mobile phones, tablets and computers. It was recently reported that presbyopia is related to difficulties with activities of daily living and resulting s...

Risk tools have matured to the point where they support a variety of risk-informed decision making. While we may expect continued development of such tools to lead to further individual improvements, we believe the greatest gains are to be had from their integration. Our work to date in connecting risk tools has had successes, but also has revealed there to be significant impediments to informa...

Accurate and complete replication of the genome in every cell division is a prerequisite of genomic stability. Thus, both prokaryotic and eukaryotic replication forks are extremely precise and robust molecular machines that have evolved to be up to the task. However, it has recently become clear that the replication fork is more of a hurdler than a runner: it must overcome various obstacles pre...