purpose: to evaluate densitometry of crystalline lens after cxl procedure in keratoconic patients. methods: in a quasi-experimental study three-dimensional lens densitometry was performed by pentacam scheimpflug camera at base line and 6 months later. subject group contained patients with diagnosed progressive keratoconus who underwent cxl surgery (n = 40). control group contained aged-matched ...

purpose: to evaluate the effectiveness of corneal collagen cross-linking with uv-a and riboflavin (cxl) for treatment of refractory herpes simplex virus necrotizing keratitis. case reports: two patients with a diagnosis of hsv necrotizing stromal keratitis referred to khalili hospital eye emergency room and who were resistant to conventional treatment underwent cxl. response to treatment was ev...

background chitosan is a naturally occurring biopolymer which has been widely used in a variety of biomedical applications including local antibiotic delivery due to its excellent mechanical properties, biodegradability and biocompatibility. beads are spherical, porous carriers which are prepared from various materials including chitosan. objectives the current study aimed to fabricate a new co...

In this research, gelatin nanoparticles were synthesized via inverse miniemulsion method by employing a mixture of a water soluble carbodiimide (CDI) and N-hydroxysuccinimide (NHS) as a non-toxic cross-linking system. The gelatin nanoparticles were characterized for their size and size distribution, morphology and stability and were compared with those of nanoparticles cross-linked by glutarald...

Nanocomposite hydrogels were developed by cross-linking nanofibrillated cellulose with poly(methyl vinyl ether-co-maleic acid) and polyethylene glycol. The cross-linked hydrogels showed enhanced water absorption and gel content with the addition of nanocellulose. In addition, the thermal stability, mechanical strength, and modulus increased with an increase in the amount of nanocellulose in hyd...

In our previous work, the effect of use of a water soluble CDI/NHS system as nontoxic cross-linking agent on fabrication of gelatin nanoparticles was investigated. In this research, the effect of variation in some synthetic parameters of gelatin nanoparticles cross-linked by CDI/NHS system such as type of gelatin and formulation of cross- linking agent on their size and distribution was examine...