نتایج جستجو برای: inactive dynamics
تعداد نتایج: 468961 فیلتر نتایج به سال:
A Ru(bpy)3Cl2 photocatalyst is applied to the rapid trans cis isomerization of a range alkene-containing pharmacological agents, including combretastatin A-4 (CA-4), clinical candidate in oncology, and resveratrol derivatives, switching their configuration from inactive substances potent cytotoxic agents. Selective cellulo activation CA-4 analog Res-3M demonstrated, along with its cytotoxicity ...
The improper activation of the Abl tyrosine kinase results in chronic myeloid leukemia (CML). The recognition of an inactive conformation of Abl, in which a catalytically important Asp-Phe-Gly (DFG) motif is flipped by approximately 180 degrees with respect to the active conformation, underlies the specificity of the cancer drug imatinib, which is used to treat CML. The DFG motif is not flipped...
Background Omentin-1 is an adipokine, mainly produced by visceral adipose tissue that improves insulin resistance. Objective This study compared the serum levels of omentin-1 and insulin resistance markers in active-obese, inactive-obese and inactive normal-weight men. Methods In this cross-sectional study, 45 men (35.0±4.2 years, no symptoms of illness) were assigned to active-obese (n=16, ...
Online Social Communities (OSCs) provide a medium for connecting people, sharing news, eliciting information, and finding jobs, among others. The dynamics of the interaction among the members of OSCs is not always growth dynamics. Instead, a decay or inactivity dynamics often happens, which makes an OSC obsolete. Understanding the behavior and the characteristics of the members of an inactive c...
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