Phenotypic differences in analgesic sensitivity to codeine (3-methoxymorphine) results from polymorphisms in cytochrome P450-2D6, which catalyzes O-demethylation of codeine to morphine. However, O-demethylation reportedly is not required for analgesic activity of the 7,8-saturated codeine congeners dihydrocodeine, hydrocodone, and oxycodone. This study determined the potency and efficacy of the...

in order to evaluation the effect of mixed cropping on yield and agronomical characteristics of wheat (triticum aestivum l.) varieties, a field experiment based on a randomized complete block design with four replications was carried out at city of mahvelat in khorasan razavi province, iran, during growing season of 2007-2008. treatments including five sole cultures of conventional wheat cultiv...

background: alpha particle irradiation from radon progeny is one of the major natural sources of effective dose in the public population. oncogenic transformation is a biological effectiveness of radon progeny alpha particle hits. the biological effects which has caused by exposure to radon, were the main result of a complex series of physical, chemical, biological and physiological interaction...

to study the effects of biological and manure fertilizer on quantity and quality characteristics of roselle (hibiscus sabdariffa l.), an experiment was conducted as split plot based on a randomized complete block design with three replications at the agricultural research center of zabol university, iran during growing season of 2012-2013. treatments included three manure level; 0, 10 and 20 t....

the continuous addition of industrial, municipal, and agricultural effluents to the environment has led to a great increase of toxic pollutants. it is well known that these pollutants are hazardous to animals, plants, microorganisms, and other living organisms including humans. as a result, effective technologies should be developed to remove these contaminants. biological remediation, as an...