• The tissue-clearance technique as a measure of effective blood flow through a tissue is obviously indirect, and the interpretation of results is necessarily based on the validity of several assumptions. One assumption is that injection into a "muscle" labels the fluid in a single uniform tissue, i.e., no connective tissue is involved. A second assumption is that clearance rate is relatively i...

Chromatographic and spectrophotometric methods for the estimation of mebendazole in pharmaceutical products were developed. The flow injection method was based on oxidation by a known excess sodium hypochlorite at pH=9.5. is then reacted with chloranilic acid (CAA) to bleach out its color. absorbance CAA recorded 530 nm. fast, simple, selective, sensitive. chromatographic carried Varian C18 col...

Imaging of the postoperative meniscus is a challenge. Nevertheless, magnetic resonance imaging (MRI) of the symptomatic knee after meniscal surgery is a valuable diagnostic study of both the menisci and the entire joint. At present, symptomatic patients who have had partial meniscectomy of less than 25% may be evaluated by MRI. For those with partial meniscectomy of greater than 25% or after me...

Receptor for advanced glycation end-products (RAGE) is a marker of alveolar type I cells and is elevated in the pulmonary edema fluid of patients with acute lung injury (ALI). We tested the hypothesis that RAGE in the bronchoalveolar lavage (BAL) would be elevated in experimental models of direct ALI characterized by alveolar epithelial cell injury. We developed ELISA measurements for RAGE and ...

BACKGROUND We have previously found that CD4(+)CD25(+) regulatory T cells (Tregs) can adoptively transfer tolerance after its induction with costimulatory blockade in a mouse model of murine cardiac allograft transplantation. In these experiments, we tested an hypothesis with three components: (1) the Tregs that transfer tolerance have the capacity for linked suppression, (2) the determinants t...

Recent success in pancreatic islet allotransplantation has raised expectations but has equally highlighted the acute shortage of donor tissue. The use of xenogeneic tissue would help to address this shortage; however, strong cellular immunity limits the application of this approach. T-cell responses to xenogeneic tissues involve recognition of intact species-mismatched major histocompatibility ...

Transition metal dichalcogenides (TMDCs), such as MoS2 and WSe2, are free of dangling bonds and therefore make more "ideal" Schottky junctions than bulk semiconductors, which produce Fermi energy pinning and recombination centers at the interface with bulk metals, inhibiting charge transfer. Here, we observe a more than 10× enhancement in the indirect band gap photoluminescence of transition me...