Particles suspended in fluid flow through a closed duct can focus to specific stable locations the cross-section due hydrodynamic forces arising from inertia of disturbed fluid. Such particle focusing is exploited biomedical and industrial technologies separate particles by size. In curved ducts, result balance between two dominant on particle: (i) inertial lift small fluid, (ii) drag cross-sec...

Inertial microfluidics has emerged as an important tool for manipulating particles and cells. For a better design of inertial microfluidic devices, we conduct 3D direct numerical simulations (DNS) and experiments to determine the complicated dependence of focusing behaviour on the particle size, channel aspect ratio, and channel Reynolds number. We find that the well-known focusing of the parti...

Exosomes are important biomarkers for clinical diagnosis. It is critical to isolate secreted exosomes from bodily fluids such as blood, saliva, breast milk, and urine liquid biopsy applications. The field of microfluidics provides numerous benefits biosample processing, diagnostics, prognostics. Several microfluidics-based methods have been employed the isolation purification in last ten years....

In this study, neural cell sorting of high throughput and high purity is made using two-step separation by combining soft inertial microfluidics and pinched flow fractionation. Both finite element analysis tool and equivalent electric circuits modeling were used to design the microfluidic devices. Separation between neurons and glia cells from rat’s spine cord was demonstrated. To minimize the ...