Recently an epidemic of diarrhea occurred in the nursery of a children's home. An organism classified as Bacillius mctllCosuts capsulatuts was present in large numbers in cultures of the stools of the sick infants. Following convalescence of the patients the organisms were not recovered from the stools. The identity of the bacterium isolated in this epidemic has not been established, but it is ...

The significance of acute diarrheal illness, a common disorder in infants and children, is presented. Although in developed countries this disease is seldom fatal, it is the second most common reason that children are hospitalized. Methods for managing acute diarrhea and its subsequent dehydration, including intravenous rehydration and refeeding, are discussed, with emphasis placed on the use o...

Although Pseudomonas aeruginosa is not generally considered as a cause of antibiotic-associated diarrhea, several cases of diarrhea caused by P. aeruginosa have been reported. We experienced seven cases of nosocomial diarrhea presumably caused by P. aeruginosa, which was the predominant organism isolated from stool cultures. Clostridium difficile toxin was also positive in one patient. No other...

From instances of diarrhea of the newborn in four separate hospital outbreaks a filtrable agent was isolated which regularly produced diarrhea in calves. This agent appeared to have the characteristics of a filtrable virus. The four strains of virus isolated in the outbreaks studied appeared to be identical or very closely related. The virus was not found present in the stools of any of eight n...

Group A Rotavirus (RVA) remains a leading cause of severe diarrhea and child mortality. The variable domain of camelid heavy chain antibodies (VHH) display potent antigen-binding capacity, have low production costs and are suitable for oral therapies. Two sets of anti-RVA VHHs have been developed: ARP1-ARP3; 2KD1-3B2. Here, we explore the potential of both sets as a prevention strategy compleme...