Male infertility is a worldwide medical problem. Asthenozoospermia is a common cause of infertility. Epigenetic modifications of DNA and histones have been shown to influence human infertility, but no research has explored whether N(6)-methyladenosine (m(6)A) level in RNA is associated with asthenozoospermia. Here, we collected a total of 52 semen samples, including 20 asthenozoospermia patient...

BACKGROUND A New Zealand randomized trial has shown that lipiodol treatment enhances fertility with high short-term effectiveness for women with endometriosis. METHODS An open randomized trial in a single-centre secondary- and tertiary-level infertility service assessing lipiodol flushing versus no intervention. A total of 158 women with unexplained infertility (62 women with mild endometrios...

A total of 811 intrauterine insemination (IUI) cycles in which clomiphene citrate/human menopausal gonadotrophin (HMG) was used for ovarian stimulation were analysed retrospectively to identify prognostic factors regarding treatment outcome. The overall pregnancy rate was 12.6% per cycle, the multiple pregnancy rate 13.7%, and the miscarriage rate 23.5%. Logistic regression analysis revealed fi...

OBJECTIVES The most common indication for treatment of varicocele is still male subfertility. The aim of this study was to explore the effect of infertility duration on semen parameters and spontaneous pregnancy rate after varicocelectomy. MATERIALS AND METHODS The medical records of 183 infertile patients with clinical varicocele were retrospectively reviewed. The patients were divided into ...

Endometriosis is a pathology that commonly prevails in more than 50% of women as cause dysmenorrhea and infertility we can define it the presence endometrial glands stroma outside it, is, ectopic tissue mostly located ovaries, Douglas pouch, uterosacral ligaments other anatomical sites. Infertility associated with endometriosis multifactorial disease there no certainty about mechanisms by which...

Objective: To verify the current practice of postponing laparoscopy after a normal HSG in infertile couples with no evident cause of infertility, aiming at reducing the need for interventional investigations thus decreasing cost and risk. Study Design: Case series study including three hundred and thirty women. Patients and Methods: The women were categorized into two groups as follows: Group (...

success rates of reproductive medical interventions. Useful may be free information sessions for patients, for example. It has been suggested that family planning and reproductive medicine aspects should be an integral part of sex education at school – just like education about contraception and prevention of sexually transmitted diseases. 5 However, it is not only infertile people who may lack...

OBJECTIVE Several publications have established a relationship between sperm DNA damage and male factor infertility, based on data from America, Europe, and Asia. This study aimed to compare the extent of sperm DNA damage in sperm samples from Nigerian men with unexplained infertility and in sperm samples from a fertile group composed of sperm donors who had successfully impregnated a female pa...

The study of sperm cellular components at molecular level is crucial for the diagnosis of male unexplained infertility. The aim of the study was to compare the molecular profile of steroid receptors and aromatase in spermatozoa obtained from two normozoospermic groups of patients issued from couples treated for infertility. We investigated 46 male patients from unexplained infertility couples a...

Background: The reported prevalence of infertility in Pakistan is 21% of which 35% is contributed by male factor. Male infertility has multifactorial etiologies ranging from modifiable to genetic risk factors. Among all the risk factors that may account for male infertility, obesity is one of the emerging public health problems. Therefore, the aim of the study was to determine the association o...