fibrates, as hypolipidemic drugs known as agonists of peroxisome proliferator-activated receptors, diminish inflammatory responses. studies have shown that incorporation of a silicon atom into a drug structure improves its pharmacological potency, modifies its selectivity toward a given target, or changes its metabolic rate, in addition to increasing the lipophilicity of the compounds. a silico...

Tooth pulpal nerves include sympathetic and sensory nerves that originate from trigeminal ganglion .From the terminal of these sensory nerves neuropeptides are secreted that are neuromodulators and neurotransmitters. One of them is CGRP (Calcitonin gene-related protein) which has a vasodilatory effect on pulpal vessels. Near abscess and moderate injuries, this neuropeptide can lead to neural fi...