Drug-induced reticulate hyperpigmentation is uncommon. Including the patient described in this report, chemotherapy-associated reticulate hyperpigmentation has only been described in ten individuals. This paper describes the features of a woman with recurrent and metastatic breast cancer who developed paclitaxel-induced reticulate hyperpigmentation and reviews the characteristics of other oncol...

Fixed drug eruption (FDE) is a unique type of cutaneous drug reaction that typically recurs in the identical locations on re-exposure to the attributed drug. FDE is characterized by the appearance of a single or multiple sharply demarcated violaceous erythematous plaques which heal with residual hyperpigmentation. A 27-year-old woman presented with multiple dark patches over her eyelids, mouth,...

amyloidosis cutis dyschromica (acd) is a rare form of macular amyloidosis characterized by hypo and hyperpigmented macules. here we described a 20 year old girl with diffuse hypo and hyperpigmentation since she was four years old. five other members of her family are also involved. biopsy of hyperpigmented lesions revealed increase of melanin in the basal layer, pigment incontinence and amorpho...

Department of Dermatology, Korea University, Ansan Hospital College of Medicine, Korea University, 516 Gojandong, Ansan-si Kyeonggi-do 425-707, Korea Salicylic acid (SA) has recently been used in higher concentrations as a superficial chemical peeling agent. The author evaluated the efficacy and safety of SA peels as a treatment of acne vulgaris in Asian people. The results prove that this peel...

Figure 1. A, Well-demarcated exophytic fungating plaque with linear keloid, peripheral crusting, and distal hyperpigmentation; B, hematoxylin-eosin stain reveals parakeratosis, pseudoepitheliomatous hyperplasia, mixed inflammatory infiltrate, and foreign body giant cells (courtesy of M. J. Zimarowski);C, hematoxylin-eosin stain of pigmented sclerotic bodies (arrow) (courtesy of M. J. Zimarowski...

Recent publications describe various skin disorders in relation with phototypes and aging. The highest (III to VI) are more sensitive acne the appearance of dark spots due inflammation induced by Cutibacterium acnes (previously named Propionibacterium acnes). Ethnic variations dryness aging a lower activity specific enzymes involved maturation lipids stratum corneum were also reported. To obser...

Post-inflammatory hyperpigmentation is common problem, but its treatment still remains challenging. Tranexamic acid has been used to treat or prevent excessive bleeding loss in various medical conditions. There have been some reports of the effect of oral and topical tranexamic acid for treatment of pigmented disorder. Herein we report on a case of female patient who showed improvement of PIH a...

BACKGROUND Hyperpigmentation disorders are common among those seeking care from dermatologists and primary care physicians. The cosmeceutical and natural product industries are rapidly growing and many botanical agents are purported to improve hyperpigmentation disorders. OBJECTIVE We sought to review clinical evidence for the use of botanical agents in the treatment of hyperpigmentation. M...