exploration of natural products with antitumoral effects such as etoposide, tenioposide, camptothecin and paclitaxel from conifers provoked us to do some research on anti-tumoral activity of iranian medicinal plants. ten different species of iranian conifers aerial parts were collected across the country. the relative potency of methanolic extract were investigated on the inhibition of topoisom...

Leptadenia reticulata was reported to be used for several medicinal purposes. The present study was undertaken to evaluate anti-inflammatory, analgesic and lipid peroxidation inhibition activities of L. reticulata. The anti-inflammatory assay was performed by λ-carrageenan and formalin induced paw edema test. Pro inflammatory mediators (IL2, IL6, TNF-α) in serum of treated and control organism ...

Protein hydrolysates and peptides can show biological activities, pulsed ultrasound improves bioactivities. Among matrices from which protein be obtain, chickpea is an excellent source. The objective of this research was to evaluate the effect on globulin concentrate obtain hydrolysate (HGb) peptide fractions their bioactivity. Antioxidant activity by ABTS (2,2′-Azino-bis(3-ethylbenzothiazoline...

Two lesser known indigenous vegetables: netlespurge (Jatropha tanjorensis) and black nightshade (Solanum nigrium) were each processed into flour samples incorporated wheat in coating peanut. These veggie peanut burgers analysed for their antioxidant properties such as DPPH, FRAP Metal Chelating ability assay linoleic acid inhibition. Veggie burger with vegetable had values between 44.62 to 68.3...

Leptadenia reticulata was reported to be used for several medicinal purposes. The present study was undertaken to evaluate anti-inflammatory, analgesic and lipid peroxidation inhibition activities of L. reticulata. The anti-inflammatory assay was performed by λ-carrageenan and formalin induced paw edema test. Pro inflammatory mediators (IL2, IL6, TNF-α) in serum of treated and control organism ...

Tuberculosis (TB) ranks second, next to AIDS making it most formidable disease if the present age. One of the crucial enzymes involved in cell wall synthesis of Mycobacterium tuberculosis, InhA (enoyl acyl carrier protein reductase) has been authenticated as an effective target for anti-mycobacterial drug development. In the current work, we have developed novel derivatives of 1,2,4-triazole-5-...

background & aim: applications of synthetic antioxidant in food have side effects. in present study, the antioxidant potential of morus alba leaves, as natural antioxidant, was screened with cupric ion reducing assay (cuprac assay) and inhibition of lipid peroxidation. the aim of this study was to determine the total antioxidant activity of morus alba leaves. martial & methods: the fir...

The present study was designed to examine the effects of Lactobacillus plantaraum and L. paracasei on the growth and aflatoxin-producing ability of Aspergillus parasiticus. In these experiments, direct and indirect interactions of two different probiotic lactobacilli with A. parasiticus was examined.A co-culture system which supported both fungal growth and probiotic bacteria showed the inhibit...

Tuberculosis (TB) ranks second, next to AIDS making it most formidable disease if the present age. One of the crucial enzymes involved in cell wall synthesis of Mycobacterium tuberculosis, InhA (enoyl acyl carrier protein reductase) has been authenticated as an effective target for anti-mycobacterial drug development. In the current work, we have developed novel derivatives of 1,2,4-triazole-5-...

The present study was aimed to enzymatic antioxidants (superoxide dismutase, catalase, polyphenol oxidase), nonenzymatic (saponin, flavonoids, ascorbic acid and tannin), anti-oxidant ability assays (total anti-oxidant, hydroxyl radical scavenging ability, reducing power activity, inhibition of lipid peroxide formation, DPPH activity metal chelating assay) in I. marginata leaves whole plant. res...