The extent and progression of exposure to feline infectious peritonitis (FIP) virus in the cheetah, Acinonyx jubatus, was monitored by a world-wide serological survey with indirect fluorescent antibody titers to coronavirus. The indirect fluorescent antibody assay was validated by Western blots, which showed that all indirect fluorescent antibody-positive cheetah sera detected both domestic cat...

Selectively facilitating apoptosis of activated T cells is essential for the clearance of pathogenic injurious cells and subsequent efficient resolution of inflammation. However, few chemicals have been reported to trigger apoptosis of activated T cells for the treatment of hepatitis without affecting quiescent T cells. In the present study, we found that asiatic acid, a natural triterpenoid, s...

The following case report describes a 1-year-old female cheetah (Acinonyx jubatus) with bilateral blindness and unresponsive pupils. For comparison, a second healthy 2.5-year-old male cheetah without visual deficits was also examined. Clinical examination of both animals included biomicroscopy, indirect ophthalmoscopy, tonometry, and electroretinography. The young female cheetah showed no menac...

Complex adnexal masses are common and often present as a diagnostic dilemma. Many of these complex adnexal masses require timely recognition and treatment. Therefore, it is important to have a good differential diagnostic approach to these lesions. The classic differential for complex adnexal mass is the mnemonic "CHEETAH." This mnemonic may be a helpful memory device for residents, especially ...

Lily tepals have a short lifespan. Once the tepals senesce, the ornamental value of the flower is lost. Some cultivars have attractive purple ovaries and fruits which greatly enhance the ornamental value of Asiatic hybrid lilies. However, little is known about the molecular mechanisms of anthocyanin biosynthesis in Asiatic hybrid lily ovaries. To investigate the transcriptional network that gov...

INTRODUCTION Cryptococcus neoformans is a saprophytic yeast that is normally found in the environment associated with organic material such a pigeon droppings and leaf litter. However, C. neoformans is a potential pathogen of both humans and animals. The infectious particle, the basidiospore, is adapted for air dispersal and has properties that allow it to adhere to and penetrate the respirator...

This study first investigates the anticancer effect of asiatic acid in two human breast cancer cell lines, MCF-7 and MDA-MB-231. Asiatic acid exhibited effective cell growth inhibition by inducing cancer cells to undergo S-G2/M phase arrest and apoptosis. Blockade of cell cycle was associated with increased p21/WAF1 levels and reduced amounts of cyclinB1, cyclinA, Cdc2, and Cdc25C in a p53-inde...

Abstract Although cheetahs Acinonyx jubatus were once widespread in the Horn of Africa, their presence Somaliland has not been confirmed since 2010, and they have presumed extirpated recent years. During 2021–2022 Cheetah Conservation Fund Ministry Environment Climate Change carried out two rapid surveys Awdal region western to investigate status cheetah this area. The team collected socio-ecol...

Matrix population models are a common tool for evaluating different management strategies. In general, under deterministic analyses, management strategies are recommended that improve those matrix transitions that are most sensitive or elastic with respect to the asymptotic population growth rate, k. These recommendations usually ignore the biological limit for these transitions. In this paper ...

Re-introduction programs rely on reproductively sound individuals and high offspring survival once captively bred species are released into their natural habitat. Some species involved in captive breeding programs reproduce poorly: one prominent example is the cheetah (Acinonyx jubatus). Here we use the cheetah as a case study to test predictions from all current hypotheses explaining this phen...