background polycystic ovary syndrome (pcos) is a common disease in young women that is associated with infertility and other complications such as obesity, hirsutism and insulin resistance and also the disorder that mostly is specified with oligomenorrhoea or amenorrhea with clinical or laboratory evidence of hyperandrogenemia. objectives the purpose of this study was to investigate whether mea...

Introduction: Gestational Diabetes Mellitus (GDM) is one of the complications of pregnancy that has some maternal and neonatal outcomes. Some drugs such as insulin and oral agents (metformin, ...) are used for management of GDM. The aim of this study was to compare metformin and insulin in treatment of GDM Methods: This clinical trial was carried out in 2009-2011. Sample size was 201 patient...

Results: Twelve articles about misconceptions and myths related to insulin therapy in Latinos or Hispanics with diabetes met the inclusion criteria. All of them evaluated misconceptions about insulin therapy using different types of interviews and questionnaires. Negative attitudes about insulin therapy were highly prevalent among Latino patients. Many considered that insulin therapy was relate...

abstract background: acute coronary syndrome is the most common disease in the world. several studies suggest that hyperglycemia is associated with poor clinical outcomes in patients with coronary artery disease. the aim of this study was to investigate the impact of insulin infusion protocol and conventional therapy on the blood glucose level and outcomes in acute coronary syndrome patients wi...

the aim of this study was to investigate the effects of 12 weeks of walking on plasma levels of leptin in postmenopausal women with breast cancer. nineteen postmenopausal women with breast cancer (age: 55.05+2.7 years) who received surgery, chemotherapy and radiation-therapy and were receiving hormone therapy by letrozol were divided into two groups: control (n=8) and experimental (n=11). subje...

Background: Insulin and metformin have been used extensively in the management of gestational diabetes mellitus (GDM).Insulin has primary medical treatment if maternal glucose targets are not achieved by dietary therapy.Insulin is safe for fetus, because it does normally cross placenta. oral antidiabetic agents, glibenclamideand most studied agents to treat GDM patients.Objective: To examine If...

The effects of systemic insulin administration at different concentrations on the testicular tissue diabetic adult rats, induced by streptozotocin, are evaluated morphological analysis spermatogenic process. Twenty-four male rats were divided into 1) Control Group: they received citrate buffer, intraperitoneal injection; 2) Diabetic injection streptozotocin (60 mg. kg-1 body weight); 3) Insulin...

introduction: obesity and visceral fat accumulation after menopause are associated with insulin resistance and cardiovascular diseases. we investigated the interactive effect of aerobic-resistance training and estrogen replacement therapy on visceral fat, omentin-1 and homa-ir in ovariectomized rats. materials and methods: fifty female wistar rats were ovariectomized (ovx) and divided into 5 gr...

Background and Aim: Diabetes is a common disorder worldwide, and exhaustive efforts have been made to cure this disease. Gene therapy has considered as a potential curative method that has more stability in comparison with the other pharmaceutical methods. However, the application of gene therapy as a definitive treatment demands further investigation. This study aim is to prepare a suitable hi...