Due to respiratory motion, lung tumor can move up to several centimeters. If respiratory motion is not carefully considered during the radiation treatment planning, the highly conformal dose distribution with steep gradients could miss the target. To address this issue, the common strategy is to add a population-derived safety margin to the gross tumor volume (GTV). However, during a free breat...

Background: Breast conserving surgery (BCS) followed by radiotherapy (RT) has been widely accepted as the standard treatment in early stages of invasive breast cancer. The standard technique of RT includes whole breast irradiation (WBI). Additional tumor bed boost irradiation has also an important role in the local tumor control. But there are various controversial delivery methods. The aim of ...

This paper introduces 3-D liver segmentation method for selective internal radiation treatment as the treatment for liver tumors. In treatment of liver cancer, delivering maximum radiation dose to the tumor and minimum toxicity to the surrounding healthy tissue is of great difficult in clinical practice. This can be eliminated by 3-D segmentation method for accurate calculation of functional tu...

OBJECTIVES Considering the fact that the standardized uptake value (SUV) of a normal lung tissue is expressed as x±SD, x+3×SD could be considered as the threshold value to outline the internal tumor volume (ITV) of a lung neoplasm. METHODS Three hollow models were filled with 55.0 kBq/mL fluorine-18 fluorodeoxyglucose (18F-FDG) to represent tumors. The models were fixed to a barrel filled wit...

background: inclusion of inhomogeneity corrections in intensity modulated small fields always makes conformal irradiation of lung tumor very complicated in accurate dose delivery. objective: in the present study, the performance of five algorithms via monte carlo, pencil beam, convolution, fast superposition and superposition were evaluated in lung cancer intensity modulated radiotherapy planni...

Background: To determine which radiotherapy parameters are associated with the tumor response of locally advanced non-small cell lung cancer (NSCLC) patients undergoing concurrent chemoradiotherapy. Materials and Methods: Thirty one patients with IIIA/IIIB NSCLC underwent chemoradiotherapy with a median dose of 63 Gy. On our actual treatments, we made radiotherapy planning to cover the planning...