rt-PA Recombinant tissue plasminogen activator SK Streptokinase UK Urokinase Pro-UK Prourokinase TNK Tenecteplase MCA Middle cerebral artery IU International units ICH Intracerebral hemorrhage PET Positron emission tomography IV Intravenous IA Intra-arterial d: Days Chapter 2 The March of Thrombolytic Therapy for Acute Ischemic Stroke to Clinical Trials: Pre-clinical Thrombolysis and Adjuncts t...

INTRODUCTION Vasospasm still is a major cause of morbidity after aneurysmal subarachnoid hemorrhage. The purpose of this report is to describe the successful management of severe refractory vasospasm with continuous intra-arterial nimodipine (IAN) treatment. CASE DESCRIPTION A 72-year old right handed woman was admitted with non-traumatic SAH WFNS grade 1. Cerebral computed tomography demonst...

Vasospasm (VSP) is one of the major causes for prolonged neurologic deficit in patients with aneurysmal subarachnoid hemorrhage. Few case series have reported about continuous local intra-arterial nimodipine administration (CLINA) in refractory VSP. We report our experience with CLINA in a patient with refractory cerebral VSP.

Spontaneous Intra-cerebral Hemorrhage (ICH) is considered a great public health problem, accounting for 9-25% of all strokes [1], 20-30% of all strokes among Asian populations [2]. The medical and or surgical treatment of spontaneous ICH appears to be a matter of controversy [3]. Spontaneous ICH can be distinguished as Primary and Secondary or Lesional and Nonlesional (based on the causative fa...

A new high-resolution MR (HR-MR) black-blood imaging technique has been developed that enables examination of intra-cranial arterial vessel walls. HR-MR images can show arterial wall thickening (concentric or asymmetric), atherosclerotic plaque, intramural hemorrhage, and enhancement. HR-MR shows promise for the diagnosis of several cerebrovascular diseases: Atherosclerosis Arteritis Reversible...

background: cerebral vasospasm is a preventable cause of death and disability in patients who experience aneurysmal subarachnoid hemorrhage (sah). the aim of this study is to investigate the incidence of cerebral vasospasm following traumatic sah and its relationship with different brain injuries and severity of trauma. method s: this cross-sectional study was conducted from october 2006 to mar...

Introduction: A review of the literature yielded 11 supratentorial regions of interest (ROI) related to swallowing in healthy individuals. To assess the relevance of these structures for transient or prolonged dysphagia we performed a lesion study in ischemic stroke patients. Methods: Atlas-based localization analysis was performed using Talairach alignment of brain scans in consecutive patient...

traumatic basal ganglia hematoma is a rare condition defined as presence of hemorrhagic lesions in basal ganglia or adjacent structures suchas internal capsule, putamen and thalamus. bilateral basal ganglia hematoma are among the devastating and rare condition. we herein report a 28-year old man, a victim of car-car accident who was brought to our surgical emergency room by immediate loss of co...

BACKGROUND AND PURPOSE Observations in human interventional stroke treatment led us to hypothesize that iodinated radiographic contrast material use may contribute to intracerebral hemorrhage. Effects of intra-arterial iodinated radiographic contrast material on hemorrhagic transformation after middle cerebral artery occlusion and reperfusion were studied in a placebo-controlled, blinded precli...

conclusions intraventricular hemorrhage followed by comatose state is a rare finding of the castor bean seed ingestion. the patient’s condition improved dramatically after ffp transfusion. introduction castor bean seed is used to control some medical conditions including diabetes mellitus due to popular belief in its effectiveness. however it may cause severe poisoning in humans and animals and...