background: the intraperitoneal injection is a common method for establishing the experimental animal model infected with parasites. the aim of this study was to investigate if the intraperitoneal injection was another route of trichinella spiralis infection. methods:  from june to july 2015, twenty balb/c mice were intraperitoneally injected with 300 t. spiralis muscle larvae in department of ...

experimental acute gastric ulcer is produced by the intraperitoneal injection of a single dose of indomethacin. acetazoleamide, a potent carbonic anhydrase inhibitor, has significantly prevented the occurrence of these ulcers. its probable mechanism is discussed.

Experimental infections with a birnavims strain isolated from turbot (Scophthalmus maximus) were conducted by immersion and intraperitoneal injection in turbot. Virus could be recovered in skin, mucus and intestine from fish infected by immersion, only up to 3 days post-infection. The distribution in internal organs was fast after intraperitoneal injection and virus was recovered with high titr...

introduction and objective: liver is an important body organ without which life is impossible. cyclophosphamide is an alkylating agent widely used as an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug. the present study aimed to find a suitable antioxidant and examine the effect of vitamin e and selenium on reducing the side effects of cyclophosphamide on liver as a vital organ....

  Occurrence of adhesions after pelvic and abdominal surgery is a well known problem. Previous surgical procedures are by far the most common cause of intra abdominal a adhesion. In over  10℅ of infertile women, adhesion formation is the main cause of their problem. Moreover postoperative adhesions are the most common cause of intestinal obstruction in the Western world. Although the cause of ...

INTRODUCTION Cyclophosphamide (CP) is alkylating agent and the most commonly used chemotherapeutic drug for various types of cancer; it causes severe toxicity. The aim of the research was to assess the protective effect of lemon fruit extract (LFE) against the side effects of the anti-cancer drug "cyclophosphamide" (CP). METHODS This experimental study was conducted in 2015. Thirty male mice ...

The aim of the present study was to determine the toxic targets of proteins from Croton tiglium L. and to investigate the potential mechanism of their toxicity. The toxic targets were determined by oral medication and intraperitoneal injection. The median lethal dose of oral medication in mice was calculated using Bliss software (2,752.8-3,407.5 mg/kg), and that of intraperitoneal injection was...

Introduction: Donepezil (DON), an Acetylcholinesterase Inhibitor (AChEI), is widely used in the treatment of Alzheimer’s Disease (AD). The current study aimed at evaluating the effect of donepezil hydrochloride on pyramidal neuron response in CA1 region of a rat model of AD. Methods: In the current experimental study, adult male Wistar rats were randomly divided into four groups: Nucleus Basal...

objective: to compare the efficacy of intravenous and intraperitoneal injection of lidocaine and normal saline in relieving postoperative pain after elective abdominal hysterectomy. materials and methods: for this double-blind randomized controlled study 109 patients undergoing elective abdominal hysterectomy were randomly allocated to three groups :1) iv group (intravenous injection group) rec...