BACKGROUND Ivermectin is widely used in veterinary practice for the treatment of ecto- and endo-parasites. In wildlife, an extra-label use this parasiticide is sometimes associated with toxicity. Different treatment regimens have been used in ivermectin toxicosis. The present report describes a successful reversal of ivermectin toxicity by intravenous administration of a commercially available ...

to evaluate the effect of intravenous infusion of a soybean based lipid emulsion (lipovenoes 10%) on some blood constituents in sheep, a replicated 2 × 2 latin square design experiment was conducted in four clinically healthy ewes. lipid emulsion (le group) or normal saline (ns group) was infused intravenously at a rate of 0.025 ml kg-1 per min for 6 hr and the concentrations of blood triglycer...

This article reports a 3-month-old baby girl with Patent Ductus Arteriosus (PDA) PDA ligation surgery, performed postoperative intercostal peripheral nerve block. Cardiac toxicity occured features of ventricular extrasystole bigeminy and AV block signs cardiac depression immediately after Administration intravenous 20% lipid emulsion, epinephrine, antiarrhythmics improved hemodynamic conditions...

1. Bologa C, Lionte C, Coman A, Sorodoc L. Lipid emulsion therapy in cardiodepressive syndrome after diltiazem overdose: case report. Am J Emerg Med 2013;3:1154.e3–4. 2. Watts TJ. The in vitro hemolytic effect of diltiazem on erythrocytes exposed to varying osmolarity. Toxicol Mech Methods 2010;20:435–9. 3. Grunbaum AM, Gilfix BM, Gosselin S, Blank DW. Analytical interferences resulting from in...

In recent years, intravenous lipid emulsion (ILE) therapy has emerged as a new rescue antidote for treatment of certain toxicities, including cyclic antidepressants, and as the primary treatment of toxic manifestations after local anesthetic exposure. We present a case of a 13-year-old girl who developed delayed seizures and cardiac arrest after amitriptyline ingestion. As part of the treatment...