Treatment of readily prepared (Z)-6-benzyloxy-1,1,1,2-tetrafluoro-6-methyl-2-hepten-4-yne with 1.5 equiv of LHMDS in -78 °C for 1 h gave the corresponding trifluoromethylated diyne in an excellent yield. This diyne was found to be a good substrate for the carbocupration with various higher-ordered cyanocuprates to give the corresponding vinylcuprates in a highly regio- and stereoselective manne...

Abstract: A reusable PdCl2(NH3)2/cationic 2,2′-bipyridyl system was used to catalyze the double Mizoroki-Heck reaction of aryl iodides with electron-deficient alkenes in water in the absence of inert gas, giving β,β-diarylated carbonyl derivatives in good to excellent yields. The formation of unsymmetrical β,β-diarylated alkenes were also studied by coupling aryl iodides with the corresponding ...

Several Hiyama cross-coupling reactions of oxasilacycloalkenes and aryl iodides are described that produce trisubstituted Z-styrenes in moderate to excellent yields. Both electron-rich and electron-poor aryl iodides are tolerated in the cross-coupling reaction. The oxasilacycloalkene coupling partners were prepared by ruthenium-catalyzed intramolecular anti-hydrosilylation of alkynols. One of t...

Microwave heating greatly accelerates Pd-catalyzed decarboxylative coupling of aromatic acids and aryl iodides, and allows the coupling of benzoic acids with unactivated arenes.

Vinyldisiloxanes equilibrate with the corresponding silanolates under basic conditions and subsequently undergo palladium catalysed cross coupling with aryl/heteroaryl iodides and bromides.

Radical chain cyclization of aryl iodides provides an efficient synthesis planar Blatter radicals, and, for the first time, access to functionalized sulphur-containing analogues.

[reaction: see text] A carbamoylsilane is shown to carry out the direct carbamoylation of aryl chlorides, bromides, and iodides under catalysis by phosphinepalladium(0) complexes.

3- And 9-component Pd(0) catalysed assembly of allenes, aryl iodides and N-nucleophiles with concomitant installation of trisubstituted Z-alkenes is readily achieved.

A transition metal-catalyzed cross-coupling reaction of cyclopropenes with aryl iodides proceeds with the opening of the cyclopropene ring, affording 1,3-butadienes as the products.