Electric field-driven translocation of DNA strands through biological nanopores has been shown to produce blockades of the nanopore ionic current that depend on the nucleotide composition of the strands. Coupling a biological nanopore MspA to a DNA processing enzyme has made DNA sequencing via measurement of ionic current blockades possible. Nevertheless, the physical mechanism enabling the DNA...

Non-linear ion transport through nanoscale structures can be used in new types of microcircuit, inspired by biological processes such as adenosine triphosphate synthesis and neural transmission. The non-linear current resulting from preferential direction of ion flow can be used for signal transmission as well as signal processing, for example, ionic current rectification and amplification as i...

The local interplay between the ionic and electronic transport in NiO is explored using correlative imaging by first-order reversal curve measurements in current-voltage and electrochemical strain microscopy. Electronic current and electromechanical response are observed in reversible and electroforming regime. These studies provide insight into local mechanisms of electroresistive phenomena in...

The current-source density analysis is a widely used method in brain electrophysiology, but this method rests on a series of assumptions, namely that current sources are exclusively made by dipoles, and that the surrounding medium is resistive and uniform. Because of these assumptions, this standard model cannot be used to estimate the contributions of monopolar sources or of non-resistive aspe...

We investigate mechanisms which could generate transient monopole signals in measuring current source density (CSD), as it had been indicated to occur in recent small volume experiments. A simple model is defined for this purpose. It is emphasized that the active nature of the neural biological activity, with its ability to generate ionic density imbalances, might be able to induce appreciable ...

In this study, we report the use of ionic liquids as modifiers in the separation of achiral and chiral analytes in micellar electrokinetic chromatography. In this investigation, polymeric surfactants and ionic liquids were added to a low-conducting buffer solution. The polymeric surfactants used in this study were poly(sodium N-undecylelinic sulfate) and poly(sodium oleyl-l-leucylvalinate). The...

in the current research, polyvinylchloride based mixed matrix heterogeneous anion exchange membranes were prepared by a solution casting technique. titanium dioxide nanoparticles were also utilized as inorganic filler additive in the membrane fabrication. the effect of tio2 nanoparticles concentration in the casting solution on the membrane physico-chemical properties was studied. membrane wate...

We explore the possibility of using thin layered semiconductor membranes for electrical control of the ion current flow through a nanopore, thereby operating like tunable ionic transistors. While single layer semiconductor membranes can be voltage tuned to operate as ionic filters or "switches", double layered membranes can rectify the ion current flowing through the nanopore in addition to ion...

The strength-interval curve plays a major role in understanding how cardiac tissue responds to an electrical stimulus. This complex behavior has been studied previously using the bidomain formulation incorporating the Beeler-Reuter and Luo-Rudy dynamic ionic current models. The complexity of these models renders the interpretation and extrapolation of simulation results problematic. Here we uti...