In this study, the complexation reaction between Alprazolam (ALP) and metal ions (Zn2+, Ni2+, Cu2+ and Co2+) was investigated by using spectrophotometry in ethanol solvent. The stoichiometry of M+/ALP complexes was calculated by applying the Job, molar ratio and Continuous Changes methods and the relevant diagrams were plotted for each metal ions in each method. The results show that the obtain...

formation of the molecular complexes between meso-tetraphenylporphyrin (tpp) and the p-acceptors 2,3-dichloro-5,6-dicyanobenzoquinone (ddq) and tetracyanothylene (tcne) in chloroform solution was investigated spectrophotometrically. the formation constants of the resulting 1:1 molecular complexes were determined using the benesi-hildebrand and nash methods. the tpp-ddq proved to be more stable ...

abstractthe ability of hesperidin (hp) to form complexes with five metals; cobalt, nickel, zinc, calcium and magnesium was investigated. the complexation was studied using u.v spectroscopic titration, in methanol as well as aqueous buffer solutions (physiological conditions). potential complexes were studied by ir and nmr spectroscopy, melting point and their solubility were also evaluated. the...

domperidone is a widely used antiemetic, poorly water soluble drug, erratically absorbed in stomach and possess several dissolution-related problems thus it has poor bioavailability. solubility of a drug plays a very important role in dissolution and hence absorption of drug which ultimately affects its bioavailability. hence, by considering the facts related to drug, attempts have been made to...

A series of heterobinuclear, thiocyanato-bridged complexes of cations [M(NH2X)6 ] 2+, and [M(en)3 ] 2+ (where X = H, Ph; M=Cu, Co, Cd, Zn) with anion [Ni(NCS)4 ] 2 –have been prepared by 1:1 molar ratio. The complexes have been characterized by FT-IR, 13C NMR and UV-vis spectroscopy, metal analysis, magnetic and conductance studies. The complexes have the following composition: [M(NH2 X)5 ][Ni(...

in this paper, two double helical dinuclear copper(ii) complexes of bis-n,o-bidentate schiff base ligands bis(3-methoxy-n-salicylidene-4,4'-diaminodiphenyl)sulfone (l1) and bis(5-bromo-n-salicylidene-4,4'-diaminodiphenyl)sulfone (l2) were prepared and characterized by elemental analyses (chn), as well as thermal analysis. elemental analyses (chn) suggested that the reaction between ligands and ...

Stabilities and quantum molecular descriptors of cyclophoshphamide (an anticancer drug)-functionalized (8,0) zigzag and (4,4) armchair carbon nanotubes (CNTs) complexes in water were studied using density functional theory (DFT) calculations. Two attachments namely the sidewall- and tip-attachments are considered for the model constructions. Calculations of the total electronic energy (Et) and ...

A new series of transition metal complexes of Co(II), Ni(II), Cu(II) and Zn(II), has beensynthesized from the Knoevenagel condensate Schiff base ligand(L) derived from β-ketoanilideand furfural with o-phenylenediamine and diethylmalonate. Structural features were determinedby spectral and analytical techniques. Square-planar geometry has been adopted by thecomplexes except cobalt complex which ...

the complexation reactions between tl+ and pb2+ ions and crown ethers 12-crown-4(12c4), 15-crown-5 (15c5), benzo-15-crown-5 (b15c5), 18-crown-6 (18c6), dicyclohexyl-18-crown-6 (dc18c6) and aza-18-crown-6 (a18c6) were studied in 90% acetonitrile and 90% ethanol solutions at 25 °c, using an a.c. polarographic technique. the stoichiometry and stability of the complexes were determined by monitorin...