PURPOSE To determine if hyperosmolar stress can stimulate human neutrophils to form neutrophil extracellular traps (NETs) and to investigate potential strategies to reduce formation of NETs (NETosis) in a hyperosmolar environment. METHODS Neutrophils were isolated from peripheral venous blood of healthy subjects and incubated in iso-osmolar (280 mOsM) or hyperosmolar (420 mOsM) media for 4 ho...

Information Security (IS) specialists’ training for all sectors of trade, industry and government has never been more important as intellectual property and other sensitive or business-critical information becomes the life-blood of many companies today. Analysis of the experience collected within training of IS specialists at the Moscow Engineering Physics Institute (State University) (the MEPh...

Objective(s) Several studies have reported improved response of exercised hearts to myocardial infarction (MI). This study was aimed to evaluate the preventive role of treadmill exercise and diosgenin on cardiac marker enzymes, thiobarbituric acid reactive substances (TBARS), total antioxidant status (TAS), lipids, and electrocardiographic (ECG) patterns in isoproterenol (ISO)-induced myocardi...

Terstappen LW. Changes in circulating carcinoma cells in patients with metastatic prostate cancer correlate with disease status. Urology 2001;58: 386 –92. vitro detection of prostate cancer circulating cells by immunocy-tochemistry, flow cytometry and RT-PCR PSA. Circulating prostate specific antigen-positive cells correlate with metastatic prostate cancer. A solid-phase enzyme-linked immunospo...

1) RFC 892 is an older version of the ISO Transport Protocol Specification. Therefore this RFC should be assumed to supercede RFC 892. 2) This document has been prepared by retyping the text of ISO/TC97/SC16/N1576 and then applying proposed editorial corrections contained in ISO/TC97/SC16/N1695. These two documents, taken together, are undergoing voting within ISO as a Draft International Stand...

Immune infertility, in terms of reproductive failure, has become a serious health issue involving approximately 1 out of 5 couples at reproductive age. Semen that is defined as a complex fluid containing sperm, cellular vesicles and other cells and components, could sensitize the female genital tract. The immune rejection of male semen in the female reproductive tract is explained as the failur...

Phospholemman (PLM), when phosphorylated at serine 68, relieves its inhibition on Na(+)-K(+)-ATPase but inhibits Na(+)/Ca(2+) exchanger 1 (NCX1) in cardiac myocytes. Under stress when catecholamine levels are high, enhanced Na(+)-K(+)-ATPase activity by phosphorylated PLM attenuates intracellular Na(+) concentration ([Na(+)](i)) overload. To evaluate the effects of PLM on NCX1 on in vivo cardia...

Dietary carotenoids show numerous biological activities, including antioxidant activity, induction of apoptosis, and inhibition of mammary cell proliferation. Studies examining the role of carotenoid consumption in relation to breast cancer recurrence are limited and report mixed results. We tested the hypothesis that breast cancer survivors with high dietary and plasma carotenoids would show s...