Androgen receptor splice variant V7 (AR-V7) was recently identified as a valuable predictive biomarker in metastatic castrate-resistant prostate cancer. Here, we report a new, sensitive and accurate screen for AR-V7 mRNA expression directly from circulating tumor cells (CTCs): We combined EpCAM-based immunomagnetic CTC isolation using the IsoFlux microfluidic platform with droplet digital polym...

This paper investigates a low-Earth orbit (LEO) satellite downlink for high-speed data communication in interference situations. A choke ring horn type antenna is used as the transmitting with an isoflux pattern LEO satellite, which has beam coverage of ±51.6° and bore-sight gain 4.4 dBi at 8 GHz. The receiving on ground station parabolic diameter 11.3 m, it half-power width (HPBW) 0.2° maximum...

in this paper, two inverse problems of stephen kind with local (dirichlet) boundary conditions are investigated. in the first problem only a part of boundary is unknown and in the second problem, the whole of boundary is unknown. for the both of problems, at first, analytic expressions for unknown boundary are presented, then by using these analytic expressions for unknown boundaries and bounda...

In this paper we describe and analyze some modified boundary element methods to solve exterior boundary value problems for the Helmholtz equation with either Dirichlet or Neumann boundary conditions. The proposed approach avoids spurious modes even in the case of Lipschitz boundaries. Moreover, the regularisation is done based on boundary integral operators which are already available in standa...

An analytic solution is presented describing ̄ow to a drain in a semi-in®nite domain bounded by a leaky layer of constant thickness. The solution is developed by applying the method of images to two parallel boundaries: an inhomogeneity boundary and an equipotential boundary. It is then demonstrated that the solution for the problem with the leaky layer approximated by a leaky boundary (a mixed...

A boundary element method has been developed for the analysis of 3D eddy current problems. This method is based on the boundary integral equation formulation with equivalent electric and magnetic currents and electric charge as unknowns. Linear shape functions, defined parametrically over a quadrilateral element, have been selected for the Galerkin’s method.

in this paper we study the boundary layer problems in which boundary conditions are non-local. here we try to find the necessary conditions by the help of fundamental solution to the given adjoint equation. by getting help from these conditions, at first the boundary condition is changed from non-local to local. the main aim of this paper is to identify the location of the boundary layer. in ot...